[人类免疫缺陷病毒(HIV):综述]。

Zeitschrift fur Hautkrankheiten Pub Date : 1990-07-01
T F Schulz, C Larcher, M P Dierich
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摘要

自1983年发现人类免疫缺陷病毒(HIV)以来,人们积累了大量关于它的知识。本文就目前对该病毒的结构、分子生物学和细胞趋向性所知的情况作一简要综述。我们讨论了它与其他慢病毒的关系以及它可能的起源;此外,我们还提到了对HIV的免疫反应及其与受感染宿主的相互作用。我们还简要总结了在生产艾滋病毒疫苗的努力中遇到的困难,并着重介绍了在研制这种疫苗方面的一些有希望的办法。
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[Human immunodeficiency virus (HIV): a review].

Since its discovery in 1983, a lot of knowledge about the human immunodeficiency virus (HIV) has been accumulated. Our paper gives a brief survey on what is known at present about the structure, molecular biology, and the cell tropism of this virus. We discuss its relationship to other lentiviruses as well as its possible origin; in addition, we refer to the immune response to HIV and its interactions with the infected host. We also briefly summarize the difficulties encountered in the attempts to produce a vaccine against HIV and highlight some promising approaches in the development of such a vaccine.

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