{"title":"[消毒剂对表皮朗格汉斯细胞的影响——提高皮肤耐受性的可能性]。","authors":"R Laub, M Möhring, C Beyer, N Welsch","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The aim of this paper is the characterization of the skin tolerance to several desinfectants. For that reason, guinea pig epidermis was treated for 1, 7 and 14 days with conventional working dilution of peracetic acid-containing and phosphoric acid-containing desinfectants. In addition, buffered desinfectants were applied. In all cases, the exposure to desinfectants causes a disappearance of histochemically detectable Langerhans cells in the treated epidermis. The lowest number of Langerhans cells was encountered after the application of Wofasteril. The buffering of the working dilution causes significantly lower (p = 0.01) damages in the Langerhans cell population. Possibilities for improving the skin tolerance of this desinfectant in normal use could result.</p>","PeriodicalId":76839,"journal":{"name":"Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete","volume":"36 10","pages":"558-60"},"PeriodicalIF":0.0000,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The effect of disinfectants on epidermal Langerhans cells--possibilities for the improvement of skin tolerance].\",\"authors\":\"R Laub, M Möhring, C Beyer, N Welsch\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The aim of this paper is the characterization of the skin tolerance to several desinfectants. For that reason, guinea pig epidermis was treated for 1, 7 and 14 days with conventional working dilution of peracetic acid-containing and phosphoric acid-containing desinfectants. In addition, buffered desinfectants were applied. In all cases, the exposure to desinfectants causes a disappearance of histochemically detectable Langerhans cells in the treated epidermis. The lowest number of Langerhans cells was encountered after the application of Wofasteril. The buffering of the working dilution causes significantly lower (p = 0.01) damages in the Langerhans cell population. Possibilities for improving the skin tolerance of this desinfectant in normal use could result.</p>\",\"PeriodicalId\":76839,\"journal\":{\"name\":\"Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete\",\"volume\":\"36 10\",\"pages\":\"558-60\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The effect of disinfectants on epidermal Langerhans cells--possibilities for the improvement of skin tolerance].
The aim of this paper is the characterization of the skin tolerance to several desinfectants. For that reason, guinea pig epidermis was treated for 1, 7 and 14 days with conventional working dilution of peracetic acid-containing and phosphoric acid-containing desinfectants. In addition, buffered desinfectants were applied. In all cases, the exposure to desinfectants causes a disappearance of histochemically detectable Langerhans cells in the treated epidermis. The lowest number of Langerhans cells was encountered after the application of Wofasteril. The buffering of the working dilution causes significantly lower (p = 0.01) damages in the Langerhans cell population. Possibilities for improving the skin tolerance of this desinfectant in normal use could result.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
