综述文章:维生素D的生理特性和功能

Lamiaa Saoud Abbod AL-anbagi, Rafah Oday Hussaein
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引用次数: 0

摘要

当7-脱氢胆固醇暴露在紫外线下时,一种叫做皮肤D3的激素原就产生了。由于它具有生物惰性,必须首先转化为25-羟基维生素d。D3必须首先在肾脏中转化为1,25-二羟基维生素D3。1,25-二羟基维生素D3激素具有一系列功能,可与核受体相互作用,包括钙浓度、肠磷酸盐浓度、骨钙动员和肾钙重吸收。它在体内还有许多其他的非钙性用途。本文就维生素D的生理、内分泌和分子生物学特性作一综述。
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Review Article: Vitamin's D Physiologic Properties and Functions
When 7-dehydrocholesterol is exposed to ultraviolet light, a prohormone called In the skin D3 is created. Being biologically inert, it must first be changed into 25-hydroxyvitamin D. D3 must first be converted to 1,25-dihydroxyvitamin D3 in the kidney formerly usage. The 1,25-dihydroxyvitamin D3 hormone, which has an array of functions, interacts with a nuclear receptor, includes calcium concentration, intestinal phosphate concentration, and bone calcium mobilization, and kidney calcium reabsorption. There are numerous additional noncalcemic uses for it in the body. In this review, physiological, endocrinologic, and molecular biologic properties of vitamin D are briefly discussed.
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