青年代谢综合征患者左右心室收缩功能与心肌应变的关系

S. Y. Bartosh-Zelenaya, V. V. Stepanova, N. E. Pavlova, O. P. Mamaeva, S. G. Sherbak
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引用次数: 0

摘要

本文的目的是根据国际糖尿病联合会(IDF)的标准,评估年轻人(18至44岁)的左、右心室收缩功能和测量心肌应变,并根据新建立的代谢综合征(MS)的临床和实验室诊断,以识别可能的心肌功能障碍的早期标志物。所有患者均接受标准的经胸超声心动图(EchoCG),评估左心室和右心室(LV和RV)的收缩功能。利用斑点跟踪二维和四维超声心动图检测心室心肌功能障碍的早期标志物,并研究MS主要成分与超声心动图参数之间的关系。通过对比分析,统计数据显示,与对照组相比,主组在2D和4D的左、右心室整体纵向应变较低。MS患者左心室总圆形应变(GCS)、径向应变(GRS)和总面积应变(GAS)的平均值也显著低于对照组。肥胖疾病指标(体重、腰围)与射血分数(EF)、心室应变参数呈负相关。
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Systolic function of the left and right ventricles and myocardial strain in young adults with metabolic syndrome
The purpose of this article is to evaluate the systolic function of the left and right ventricles and measure myocardial Strain in young people (from 18 to 44 years old) with a newly established clinical and laboratory diagnosis of metabolic syndrome (MS) according to the criteria of the International Diabetes Federation (IDF), to identify possible early markers of myocardial dysfunction. All patients underwent standard transthoracic echocardiography (EchoCG) with assessment of systolic function of the left and right ventricles (LV and RV). The work detects early markers of ventricular myocardial dysfunction using speckle tracking 2D and 4D EchoCG, and also investigates the relationship between the main components of MS and echocardiographic parameters. With the help of a comparative analysis, statistical data were revealed on the low global longitudinal strain of the left and right ventricle in 2D and 4D in the main group compared with the control group. In individuals with MS, the mean values of global circular strain (GCS), radial (GRS) strain and global area strain (GAS) of the left ventricle were also significantly lower than the control group. Indicators obesity diseases (body weight and waist circumference) had a negative correlation with the ejection fraction (EF) and parameters of ventricular strain.
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