巨大胃囊性胃肠道间质瘤的罕见表现

Nihan TURHAN, Didem ERTORUL, Elbrus ZARBALİYEV, Safak COSKUN, Dilek YILMAZ
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摘要

胃肠道间质肿瘤(gist),由Cajal间质细胞引起的非上皮间质肿瘤。gist的诊断工具是酪氨酸激酶生长因子受体(c-KIT / CD117)的表达。它们最常发生在胃部。这里我们报告一个罕见的GIST病例,表现为一个大的囊性肿块,与主要肿瘤相连,有一个结节。女,44岁,因腹痛、肠梗阻就诊于急诊科。急诊腹腔镜检查发现一个直径约25厘米的囊性肿块。病理诊断为胃肠道间质瘤伴囊性变性。肿瘤内有坏死区,有丝分裂指数高,c-KIT阳性,直径大。囊性胃肠道间质瘤预后不良,术后应密切随访。
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An Unusual Presentation of Huge Gastric Cystic Gastrointestinal Stromal Tumor
Gastrointestinal stromal tumors (GISTs), nonepithelial, mesenchymal tumors arising from the interstitial cells of Cajal. The diagnostic tool for the GISTs is tyrosine kinase growth factor receptor (c-KIT / CD117) expression. They most commonly occur in the the stomach. Here we reported a rare case of GIST, presenting as a large cystic mass connected to the main tumor with a peduncle. A 44-year-old female patient presented to the emergency department with abdominal pain and intestinal obstruction. Emergency laparatomy revealed a cystic mass of approximately 25 cm in diameter. The pathological diagnosis was gastrointestinal stromal tumor with cystic degenaration. Tumor contained areas of necrosis, high mitotic index, c-KIT positive and was large in diameter. Cystic GISTs have poor prognostic factors and patients should be followed closely in the postoperative period.
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