慢性心力衰竭患者与COVID-19:关注心肌损伤的实验室标志物

N. V. Bagisheva, M. V. Moiseeva, A. V. Mordyk, V. V. Streltsova, E. P. Antipova
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摘要

研究的目的。确定CHF患者当前COVID-19的严重程度。材料和方法。该研究包括来自98名被诊断为COVID-19合并CHF的患者的数据。对住院时间、病变严重程度、实验室参数动态水平等数据进行了分析。结果。在68例CHF 2A患者中,27例患者为I期CHF, 3例患者为0期。功能级CHF I - 23例,FC II - 73例,FC III - 2例。平均住院时间为15天。75例患者血饱和度(SpO2)在95 - 100%范围内,20例90 - 95%,3例低于90%。在42.86%的患者中,根据实验室研究检测到d -二聚体水平升高。结论。伴有明显临床症状的60岁及以上CHF 2A和FC II患者存在严重感染风险,需要住院治疗。心血管系统的伴随疾病增加了住院时间。
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Chronic heart failure patient and COVID-19: Focus on laboratory markers of myocardial damage
The aim of the study. To determine the severity of the current COVID-19 in patients with CHF. Materials and methods. The study included data from 98 patients diagnosed with COVID-19 in combination with CHF. The data on the duration of hospitalization, the severity of the lesion, the dynamics of the level of laboratory parameters are analyzed. Results. In 68 patients with CHF 2A, stage I of CHF in 27 patients and in 3 patients – stage 0. CHF of functional class I – 23 patients, FC II – 73 patients, FC III – 2 patients. The average duration of hospitalization was 15 days. Blood saturation (SpO2) in the range of 95–100 % was determined in 75 patients, 90–95 % – in 20 people, less than 90 % – in 3 patients. In 42.86 % of patients, an increase in the level of D-dimer was detected according to laboratory studies. Conclusions. Patients 60 years and older with CHF 2A and FC II with pronounced clinical symptoms are at risk of severe infection requiring hospitalization. Concomitant diseases of the cardiovascular system increase the duration of hospitalization.
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