三级医院慢性心力衰竭患者缺铁的患病率:一项观察性研究

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摘要

本研究是一项观察性研究,旨在探讨慢性心力衰竭(CHF)患者缺铁(ID)的患病率以及缺铁程度与慢性心力衰竭(CHF)严重程度的关系。目的:本研究的目的是评估ID的程度及其对CHF患者的不良影响。本研究旨在评估贫血和非贫血受试者中ID的患病率和效果。方法:研究对象来自诊断为CHF的opd和IPD患者,基于临床和2d回声表现。根据铁谱和转移蛋白饱和度(TSAT)诊断ID。研究期间为2017年1月至2018年3月;其中包括109名患者。在这些病例中,进行了经胸超声心动图,胸部x线检查,必要的血液生化和全血细胞计数。采用IBM SPSS 24.0软件对109例chf患者的数据进行分析。结果:86.2%的患者缺铁,40.3%为功能性ID(铁蛋白100-300,tsat小于20%),45.9%为绝对ID(铁蛋白小于100)。有趣的是,在那些没有临床或实验室贫血报告的患者中,大约四分之一的患者缺铁。结论:本研究揭示了心衰患者的ID在印度是一个被严重忽视的领域。这项研究表明,需要在印度进行大规模的研究,以便很好地描述这种容易治疗的疾病,并在我国的指导方针中引入对id的常规检测。
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Prevalence of Iron Deficiency in Chronic Heart Failure Patients in a Tertiary Care Hospital: An Observational Study
Introduction: This is an observational study to explorethe prevalence of irondeficiency (ID) and the relationshipbetween the severity of chronic heart failure (CHF) and the degree of ID in CHF patients.Objective: The objective of the study was to assess the extent of ID and its adverse effects on patients with CHF.This study was intended to assess the prevalence and effect of ID in anaemic as well as, non-anaemic subjects.Methodology: Study subjects were from OPDs and IPD patients with the diagnosis of CHF, based on clinical and2D echo findings. ID was diagnosed by basing on iron profile along with transferin saturation (TSAT). The studyperiod was from January 2017 to March 2018; from which 109 patients were included. In those cases, trans-thoracicechocardiography, chest X-Ray, necessary blood biochemistry and CBC were done. Data collected on 109 cases ofCHF were analyzed using IBM SPSS 24.0 software.Results: Iron deficiency was present in 86.2% of patients, 40.3% had functional ID (ferritin 100-300 and TSATless than 20%) and 45.9% had absolute ID (ferritin less than 100). Interestingly, out of those who had no anaemiaclinically or laboratory report wise approximately one-fourth of the patients had iron deficiency.Conclusion: This study reveals that ID in HF is a hugely ignored area in India. This study brings out the need forlarge-scale studies in India so that this easily treatable condition can be well characterized and routine testing forID could be introduced in the guidelines of our country.
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