骨髓增生异常综合征/同时累及皮肤的骨髓增生性肿瘤

Anwarul Islam
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摘要

骨髓增生异常综合征(MDS)和骨髓增生性肿瘤(MPN)被认为是一组异质性造血肿瘤,具有重叠的骨髓增生异常和骨髓增生性特征。它们主要发生在老年人中,并且具有转化为急性髓性白血病的固有倾向。MDS/MPN的病因目前仍不确定。我们的报告描述了一个MDS/MPN患者,他在发生MDS/MPN前几年也有皮肤受累(皮肤癌),这提高了他的皮肤受累可能在MDS/MPN的发展中起作用的可能性。
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"Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Simultaneous Cutaneous Involvement"
Myelodysplastic syndrome (MDS) and myeloproliferative neoplasm (MPN) are considered to be a group of heterogeneous hematopoietic neoplasms with overlapping myelodysplastic and myeloproliferative features. They occur mostly in the elderly and have an inherent tendency to transform into acute myeloid leukemia. The etiology of MDS/MPN remains uncertain at the present time. Our report describes a patient with MDS/MPN who also had cutaneous involvement (cutaneous carcinoma) several years prior to developing MDS/MPN raising the possibility that his cutaneous involvement may have played a role in the development of MDS/MPN.
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