术中冷冻切片对肺癌手术整体及时性及生存率影响的评价

Merve ŞENGÜL İNAN, Kubilay İNAN, İlknur AYTEKİN ÇELİK, Nurettin KARAOGLANOGLU
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引用次数: 0

摘要

背景/目的:我们旨在了解肺癌手术患者在这一过程中的管理是否存在延误,并了解术中冷冻切片对这一过程的影响。 & # x0D;方法:对176例患者进行分析。记录入院日期、诊断、手术和术后病理结果。5个时间间隔分别为首次评估至诊断、首次评估至手术、诊断至手术、首次评估至术后病理报告日、诊断至术后病理报告日。 & # x0D;结果:患者以男性为主(81.8%),中位年龄63岁(iqr = 11)。首次评估至最终病理检查结果的中位时间为62天(iqr = 70)。冷冻切片诊断的患者,从首发到手术的时间显著缩短(p 0.001),从诊断到最终病理的时间也显著缩短(p 0.001)。然而,两组患者从初始评估到诊断的时间差异无统计学意义(0.052)。冷冻法诊断的患者与其他方法诊断的患者的生存率无显著差异(p = 0.508)。 & # x0D;结论:通过更好地了解延迟,可以设计出提高肺癌患者护理及时性的解决方案。术中冷冻切片诊断提高了肺癌手术患者的整体及时性,但对生存率没有影响。
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Evaluation of the effect of intraoperative frozen section on overall timeliness and survival in lung cancer surgery
Background/Aim: We aimed to find out whether there is any delay in the management of the process in patients operated on for lung cancer and to understand the effect of intraoperative frozen section on this process. Methods: 176 patients were analyzed in total. The dates of admission, diagnosis, operation, and postoperative pathology results were noted. Five intervals were defined as time from first evaluation to diagnosis, first evaluation to surgery, diagnosis to surgery, first evaluation to the day of the postoperative pathology report, and diagnosis to the day of the postoperative pathology report. Results: The majority of patients (81.8%) were male, and the median age was 63 years (iqr = 11). The median time between the first assessment and the final pathological examination result was 62 days (iqr = 70). The time from initial presentation to surgery was significantly shorter (p 0.001), and the time from diagnosis to final pathology was also significantly shorter (p 0.001) in patients diagnosed by frozen section. However, there was no significant difference in the time from initial evaluation to diagnosis between the two groups (0.052). There was no significant difference in survival between patients diagnosed by freezing and patients diagnosed by other methods (p = 0.508). Conclusion: Solutions to increase the timeliness of care for patients with lung cancer can be designed with a better understanding of delays. Intraoperative frozen section diagnosis improves overall timeliness but has no effect on survival in lung cancer patients undergoing surgery.
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