低流量灌注技术治疗粗大主动脉弓。

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS General Thoracic and Cardiovascular Surgery Pub Date : 2024-07-01 Epub Date: 2023-11-23 DOI:10.1007/s11748-023-01988-7
Takashi Shuto, Hirofumi Anai, Tomoyuki Wada, Takayuki Kawashima, Kazuki Mori, Shinji Miyamoto
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引用次数: 0

摘要

背景:胸主动脉病变伴粗主动脉最常见的并发症是脑梗死。我们已经将“低流量灌注”作为体外循环的一种方法来预防主动脉弓强动脉粥样硬化病变患者的脑栓塞。方法:“低流量灌注”是一种通过部分抽血开始体外循环的方法,在保持自身心输出量的同时接近深度低温。我们比较了2019年以来主动脉弓手术中12例采用“低流量灌注”方法(L组)和12例正常体外循环(N组)的患者的结果。结果:L组男性8例,平均年龄73岁;N组男性6例,平均年龄73岁。L组从开始降温到心室颤动的平均时间为9.5 min, N组为3.6 min (p)。结论:采用该方法,心室颤动发生时颅内温度足够低,无需增加泵总流量。低流量灌注法通过防止血流射流破坏动脉粥样硬化来预防脑栓塞,同时在冷却过程中保持自身心输出量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Low-flow perfusion technique for shaggy aortic arch.

Background: The most common complication of thoracic aortic disease with shaggy aorta is cerebral infarction. We have performed "low-flow perfusion" as a method of extracorporeal circulation to prevent cerebral embolism in patients with strong atherosclerotic lesions in the aortic arch.

Methods: "Low-flow perfusion" is a method in which cardiopulmonary bypass is started by partial blood removal, approaching deep hypothermia while maintaining self-cardiac output. We compared the outcomes of 12 patients who underwent the "low-flow perfusion" method (Group L) with those of 12 who underwent normal extracorporeal circulation (Group N) during aortic arch surgery since 2019.

Results: Group L consisted of 8 males with an average age of 73 years old, and Group N consisted of 6 males with an average age of 73 years old. The average time from the start of cooling to ventricular fibrillation was 9.5 min in Group L and 3.6 min in Group N (p < 0.01). The eardrum temperature when ventricular fibrillation was reached was 28.2 °C in Group L and 32.5 °C in Group N (p = 0.01). A blood flow analysis also revealed low wall shear stress on the lesser curvature of the aortic arch.

Conclusion: With this method, the intracranial temperature was sufficiently low at the time of ventricular fibrillation, and there was no need to increase the total pump flow. The low-flow perfusion method can prevent cerebral embolism by preventing atheroma destruction by the blood flow jet while maintaining the self-cardiac output during the cooling process.

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来源期刊
General Thoracic and Cardiovascular Surgery
General Thoracic and Cardiovascular Surgery Medicine-Pulmonary and Respiratory Medicine
CiteScore
2.70
自引率
8.30%
发文量
142
期刊介绍: The General Thoracic and Cardiovascular Surgery is the official publication of The Japanese Association for Thoracic Surgery and The Japanese Association for Chest Surgery, the affiliated journal of The Japanese Society for Cardiovascular Surgery, that publishes clinical and experimental studies in fields related to thoracic and cardiovascular surgery.
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