{"title":"Assessment of clinical and biological characteristics by pathological subtypes of lung adenocarcinoma.","authors":"Kohei Abe, Jun Suzuki, Hikaru Watanabe, Satoshi Takamori, Tetsuro Uchida, Satoshi Shiono","doi":"10.1007/s11748-026-02287-7","DOIUrl":"https://doi.org/10.1007/s11748-026-02287-7","url":null,"abstract":"","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147485583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-09DOI: 10.1007/s11748-026-02279-7
Alessio Campisi, Cinzia Bonadiman, Alessandro Cipolli, Daniele Autelitano, Cristiano Benato, Giovanni Magnanelli, Giovanni Muriana, Camillo Aliberti
{"title":"Intraoperative localization of pulmonary nodules using indocyanine green-lipiodol marking: a single-center case series.","authors":"Alessio Campisi, Cinzia Bonadiman, Alessandro Cipolli, Daniele Autelitano, Cristiano Benato, Giovanni Magnanelli, Giovanni Muriana, Camillo Aliberti","doi":"10.1007/s11748-026-02279-7","DOIUrl":"https://doi.org/10.1007/s11748-026-02279-7","url":null,"abstract":"","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-05DOI: 10.1007/s11748-026-02269-9
Yujiro Yokoyama, Tomonari M Shimoda, Toshiki Kuno, Michel Pompeu Sá, Yoshihisa Miyamoto, Hisato Takagi, Shinichi Fukuhara, Tsuyoshi Kaneko
{"title":"Valve-sparing root replacement versus Bentall procedure with bioprosthetic valves in patients with aortic insufficiency: a meta-analysis.","authors":"Yujiro Yokoyama, Tomonari M Shimoda, Toshiki Kuno, Michel Pompeu Sá, Yoshihisa Miyamoto, Hisato Takagi, Shinichi Fukuhara, Tsuyoshi Kaneko","doi":"10.1007/s11748-026-02269-9","DOIUrl":"https://doi.org/10.1007/s11748-026-02269-9","url":null,"abstract":"","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To evaluate the initial clinical experience with the Saroa surgical system for pulmonary anatomical resection and to assess its perioperative safety.
Methods: This retrospective observational study included 45 consecutive patients who underwent pulmonary anatomical resection using the Saroa surgical system. Pulmonary anatomical resections included lobectomy (n = 26) and segmentectomy (n = 19). Robot-related lung and vascular injuries were defined as the safety-specific endpoints.
Results: The median age was 69 years, and 24 patients (53.3%) were male. The cohort comprised 36 patients with primary lung cancer, seven with metastatic lung tumors, and two with benign lung tumors. The median total operative time was 199 min, and the median console time was 145 min, accounting for approximately 70-75% of the total operative time. The median estimated intraoperative blood loss was 40 mL. Postoperative complications occurred in 15.6% of patients and were limited to postoperative air leaks. No perioperative mortalities were observed.
Conclusions: In this initial clinical experience, Saroa-assisted pulmonary anatomical resection was performed safely without robot-related lung or vascular injuries. This suggests that the incorporation of haptic feedback does not compromise surgical safety during early clinical use.
{"title":"Initial clinical experience with saroa, a haptic feedback-enabled surgical assist robot, in pulmonary anatomical resection.","authors":"Hironori Ishibashi, Ryo Wakejima, Ayaka Asakawa, Yusuke Sugita, Yuya Ishikawa, Kenichi Okubo","doi":"10.1007/s11748-026-02280-0","DOIUrl":"https://doi.org/10.1007/s11748-026-02280-0","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the initial clinical experience with the Saroa surgical system for pulmonary anatomical resection and to assess its perioperative safety.</p><p><strong>Methods: </strong>This retrospective observational study included 45 consecutive patients who underwent pulmonary anatomical resection using the Saroa surgical system. Pulmonary anatomical resections included lobectomy (n = 26) and segmentectomy (n = 19). Robot-related lung and vascular injuries were defined as the safety-specific endpoints.</p><p><strong>Results: </strong>The median age was 69 years, and 24 patients (53.3%) were male. The cohort comprised 36 patients with primary lung cancer, seven with metastatic lung tumors, and two with benign lung tumors. The median total operative time was 199 min, and the median console time was 145 min, accounting for approximately 70-75% of the total operative time. The median estimated intraoperative blood loss was 40 mL. Postoperative complications occurred in 15.6% of patients and were limited to postoperative air leaks. No perioperative mortalities were observed.</p><p><strong>Conclusions: </strong>In this initial clinical experience, Saroa-assisted pulmonary anatomical resection was performed safely without robot-related lung or vascular injuries. This suggests that the incorporation of haptic feedback does not compromise surgical safety during early clinical use.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-04DOI: 10.1007/s11748-026-02277-9
Buse Mine Konuk Balcı, Gökhan Kocaman, Yusuf Kahya, Bülent Mustafa Yenigün, Atilla Halil Elhan, Serkan Enön
{"title":"Total tumor size as a robust prognostic factor for pulmonary metastasectomy.","authors":"Buse Mine Konuk Balcı, Gökhan Kocaman, Yusuf Kahya, Bülent Mustafa Yenigün, Atilla Halil Elhan, Serkan Enön","doi":"10.1007/s11748-026-02277-9","DOIUrl":"https://doi.org/10.1007/s11748-026-02277-9","url":null,"abstract":"","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aimed to report "real-world" mid-term clinical experiences and outcomes after surgical mitral valve replacement with the Epic bioprosthesis in a high-volume Japanese heart center.
Methods: Patients undergoing surgical mitral valve replacement with the Epic bioprosthesis from 2012 to 2023 were enrolled. Postoperative outcomes, survival, and hemodynamic performance were analyzed. The study endpoints were all-cause mortality, freedom from mitral valve reintervention, and major adverse cardiac events.
Results: A total of 122 patients (mean age: 73 ± 8 years, 73 males) successfully underwent surgical mitral valve replacement with the Epic bioprosthesis (25 mm, n = 22; 27 mm, n = 37; 29 mm, n = 26; and 31 mm, n = 37). The primary valve etiologies were infective endocarditis (n = 17), stenosis (n = 18), stenosis and regurgitation (n = 13), regurgitation (n = 73), and thrombosis (n = 1). The median follow-up period was 33 (interquartile range: 20-48) months. Overall survival rates at 1, 3, and 5 years after mitral valve replacement were 86.8%, 82.0%, and 76.9%. The rates of freedom from rehospitalization for heart failure were 96.7% at 1 year, 95.5% at 3 years, and 91.2% at 5 years. The mean pressure gradient was 5 (interquartile range: 4-6.4) mmHg at discharge, 5.4 (interquartile range: 4.3-6.9) mmHg at 1 year, and 5.4 (interquartile range: 4-7.5) mmHg at late follow-up (Friedman test, p = 0.46). During the study period, only one patient required reintervention because of valve deterioration at 31 postoperative months.
Conclusion: The clinical outcomes of mitral valve replacement with the Epic bioprosthesis are satisfactory, with stable hemodynamics and extremely low incidence of structural valve deterioration and reintervention over 5 years.
目的：本研究旨在报道在日本一个大容量心脏中心使用Epic生物假体手术二尖瓣置换术后的“真实世界”中期临床经验和结果。方法：纳入2012年至2023年接受Epic生物假体二尖瓣置换术的患者。分析术后结果、生存和血流动力学表现。研究终点为全因死亡率、二尖瓣再介入自由和主要心脏不良事件。结果：122例患者（平均年龄：73±8岁，男性73例）成功行Epic生物假体二尖瓣置换术（25 mm, n = 22; 27 mm, n = 37; 29 mm, n = 26; 31 mm, n = 37）。主要瓣膜病因为感染性心内膜炎（17例）、狭窄（18例）、狭窄并反流（13例）、反流（73例）和血栓形成（1例）。中位随访时间为33个月（四分位数间距：20-48个月）。二尖瓣置换术后1、3、5年的总生存率分别为86.8%、82.0%和76.9%。心力衰竭再住院率1年时为96.7%，3年时为95.5%，5年时为91.2%。出院时平均压力梯度为5（四分位数范围：4-6.4）mmHg， 1年后为5.4（四分位数范围：4.3-6.9）mmHg，随访后期为5.4（四分位数范围：4-7.5）mmHg （Friedman检验，p = 0.46）。在研究期间，只有1例患者在术后31个月因瓣膜恶化而需要再次干预。结论：Epic生物假体二尖瓣置换术的临床结果令人满意，5年内血流动力学稳定，瓣膜结构恶化和再干预发生率极低。
{"title":"Mid-term outcomes and hemodynamic performances of Abbott Epic mitral bioprosthesis: a single-center study.","authors":"Takayuki Gyoten, Yu Miyama, Yu Kumagai, Yuta Kanazawa, Taiyo Kuroda, Takayuki Akatsu, Yuko Gatate, Osamu Kinoshita, Toshihisa Asakura, Akihiro Yoshitake","doi":"10.1007/s11748-025-02212-4","DOIUrl":"10.1007/s11748-025-02212-4","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to report \"real-world\" mid-term clinical experiences and outcomes after surgical mitral valve replacement with the Epic bioprosthesis in a high-volume Japanese heart center.</p><p><strong>Methods: </strong>Patients undergoing surgical mitral valve replacement with the Epic bioprosthesis from 2012 to 2023 were enrolled. Postoperative outcomes, survival, and hemodynamic performance were analyzed. The study endpoints were all-cause mortality, freedom from mitral valve reintervention, and major adverse cardiac events.</p><p><strong>Results: </strong>A total of 122 patients (mean age: 73 ± 8 years, 73 males) successfully underwent surgical mitral valve replacement with the Epic bioprosthesis (25 mm, n = 22; 27 mm, n = 37; 29 mm, n = 26; and 31 mm, n = 37). The primary valve etiologies were infective endocarditis (n = 17), stenosis (n = 18), stenosis and regurgitation (n = 13), regurgitation (n = 73), and thrombosis (n = 1). The median follow-up period was 33 (interquartile range: 20-48) months. Overall survival rates at 1, 3, and 5 years after mitral valve replacement were 86.8%, 82.0%, and 76.9%. The rates of freedom from rehospitalization for heart failure were 96.7% at 1 year, 95.5% at 3 years, and 91.2% at 5 years. The mean pressure gradient was 5 (interquartile range: 4-6.4) mmHg at discharge, 5.4 (interquartile range: 4.3-6.9) mmHg at 1 year, and 5.4 (interquartile range: 4-7.5) mmHg at late follow-up (Friedman test, p = 0.46). During the study period, only one patient required reintervention because of valve deterioration at 31 postoperative months.</p><p><strong>Conclusion: </strong>The clinical outcomes of mitral valve replacement with the Epic bioprosthesis are satisfactory, with stable hemodynamics and extremely low incidence of structural valve deterioration and reintervention over 5 years.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":"271-277"},"PeriodicalIF":1.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12956954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145388728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Critical insights into the \"Skeletal muscle volume by 3D imaging and long-term survival in esophageal squamous cell carcinoma with neoadjuvant chemotherapy\".","authors":"Memuna Jehan Zeb, Armoghan Ayub, Anum Choudhry, Numan Abdullah, Saba Mushtaq","doi":"10.1007/s11748-025-02211-5","DOIUrl":"10.1007/s11748-025-02211-5","url":null,"abstract":"","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":"326-327"},"PeriodicalIF":1.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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