{"title":"1,2 -二氧杂环[3.3.1]壬烷衍生物的非对映选择性合成","authors":"-Mediated Cascade Reactions","doi":"10.3987/com-23-14891","DOIUrl":null,"url":null,"abstract":"<span>The highly diastereoselective one-pot synthesis generating a variety of 9,9-dimethyl-2,8-dioxabicyclo[3.3.1]nonane derivatives up to </span><span>dr</span><span> >19:1 has been established by the reaction of a 2’-methoxylchalcone with isobutyraldehyde via a spontaneous sequential one-pot Michael addition/aldol reaction/demethylative bicyclization in the presence of molecular iodine. </span>","PeriodicalId":13166,"journal":{"name":"Heterocycles","volume":"137 3","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diastereoselective Synthesis of 2,8-Dioxabicyclo[3.3.1]Nonane Derivatives via I\",\"authors\":\"-Mediated Cascade Reactions\",\"doi\":\"10.3987/com-23-14891\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<span>The highly diastereoselective one-pot synthesis generating a variety of 9,9-dimethyl-2,8-dioxabicyclo[3.3.1]nonane derivatives up to </span><span>dr</span><span> >19:1 has been established by the reaction of a 2’-methoxylchalcone with isobutyraldehyde via a spontaneous sequential one-pot Michael addition/aldol reaction/demethylative bicyclization in the presence of molecular iodine. </span>\",\"PeriodicalId\":13166,\"journal\":{\"name\":\"Heterocycles\",\"volume\":\"137 3\",\"pages\":\"\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2023-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Heterocycles\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.3987/com-23-14891\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Heterocycles","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.3987/com-23-14891","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Diastereoselective Synthesis of 2,8-Dioxabicyclo[3.3.1]Nonane Derivatives via I
The highly diastereoselective one-pot synthesis generating a variety of 9,9-dimethyl-2,8-dioxabicyclo[3.3.1]nonane derivatives up to dr >19:1 has been established by the reaction of a 2’-methoxylchalcone with isobutyraldehyde via a spontaneous sequential one-pot Michael addition/aldol reaction/demethylative bicyclization in the presence of molecular iodine.
期刊介绍：
Since its inception in 1973 HETEROCYCLES has provided a platform for the rapid exchange of research in the areas of organic, pharmaceutical, analytical, and medicinal chemistry of heterocyclic compounds in addition to communications, papers, reviews, a special section of the journal presents newly-discovered natural products whose structure has recently been established.
Another section is devoted to the total synthesis of previously documented natural products with heterocyclic ring systems.
Due to the fact that the journal is able to publish articles within two months of receipt of the manuscripts, researchers in this field can obtain up-to-date information on heterocyclic research by reading Heterocycles regularly.
Audience: Organic and Physical Organic Chemists, Biochemists, Pharmacologists and Scientists studying heterocyclic compounds
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