Alvaro López Malizia, Antonela Merlotti, Pierre-Emmanuel Bonte, Melina Sager, Yago Arribas De Sandoval, Christel Goudot, Fernando Erra Díaz, Pehuén Pereyra-Gerber, Ana Ceballos, Sebastian Amigorena, Jorge Geffner, Juan Sabatte
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引用次数: 0
摘要
树突状细胞（DC）在诱导适应性免疫反应中起着关键作用。它们捕获外周组织中的抗原，为幼稚的 T 淋巴细胞提供能量，从而触发适应性免疫反应。
Clusterin protects mature dendritic cells from reactive oxygen species mediated cell death
Dendritic cells (DCs) play a key role in the induction of the adaptive immune response. They capture antigens in peripheral tissues and prime naïve T lymphocytes, triggering the adaptive immune res...
期刊介绍：
Tumor immunology explores the natural and therapy-induced recognition of cancers, along with the complex interplay between oncogenesis, inflammation, and immunosurveillance. In response to recent advancements, a new journal, OncoImmunology, is being launched to specifically address tumor immunology. The field has seen significant progress with the clinical demonstration and FDA approval of anticancer immunotherapies. There's also growing evidence suggesting that many current chemotherapeutic agents rely on immune effectors for their efficacy.
While oncologists have historically utilized chemotherapeutic and radiotherapeutic regimens successfully, they may have unwittingly leveraged the immune system's ability to recognize tumor-specific antigens and control cancer growth. Consequently, immunological biomarkers are increasingly crucial for cancer prognosis and predicting chemotherapy efficacy. There's strong support for combining conventional anticancer therapies with immunotherapies. OncoImmunology will welcome high-profile submissions spanning fundamental, translational, and clinical aspects of tumor immunology, including solid and hematological cancers, inflammation, and both innate and acquired immune responses.
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