IN VITRO evaluation of probiotic properties and bacteriocinogenic potential of strains of microorganisms L. Acidophilus 13, E. Faecium K-50 and their compositions

It is known that the gut microbiota plays a central role in the health and biology of the animal, and is therefore important for scientific research. Microorganisms of the genus Lactobacllus  are  widespread  in  nature  and are considered representatives of the microflora  of  the  macroorganism  of  the  animal. Lactobacllus acidophilus is widely used as a probiotic, and is known for its immunostimulating effect, it colonizes the intestines of a newborn  and  accompanies  the  animal throughout its life. Enterococcus faecium is also used as a probiotic, due to its high antagonistic activity against pathogenic microbiota, and also participates in the formation and maintenance of immunity. The purpose of  this  study  was  to  evaluate  the  probiotic component of L. acidophilus 13, E. faecium k-50  in  conditions  simulating  the  gastrointestinal tract, to study the bacteriocinogenic potential and antagonistic properties of lactobacilli and enterococci and their composition.  In  this  review,  we  summarize  recent advances  in  understanding  the  mechanisms involved in bacterial tolerance to bile, with particular  emphasis  on  research  contributions. In addition, the physiological and ecological role of enzymes and their importance for animal health, as well as the function of bile  acid  as  a  regulator  of metabolism,  are discussed. Samples were used in the study.