胰腺癌手术是一个中心的经验。

Nikita Mikolenko
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摘要

胰腺癌是一种源自胰腺上皮的恶性肿瘤。尽管不断努力和深入研究,但仍无法确定对胰腺癌的早期诊断和治疗效果有重大影响的风险因素。2021 年,俄罗斯联邦共发现 15055 名胰腺癌患者,其中 III 期患者占 16.9%,IV 期患者占 58.2%。确诊后第一年的死亡率为 65.1%。共有 1856 名患者接受了根治性手术治疗。前列腺癌临床表现的特点:潜伏期长,与慢性胰腺炎临床表现相似,可导致疾病诊断较晚。约 70% 的病例表现为机械性黄疸综合征,这需要额外的侵入性诊断和治疗方法。在诊断核实时,80%-85% 的患者已经因肿瘤局部或远处扩散而无法手术。无法切除的胰腺癌患者的平均预期寿命约为 6-7 个月。根据不同学者的研究结果,经过根治性手术治疗后,该病理类型患者的 5 年生存率在 0% 到 30% 之间。
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Pancreatic cancer surgery is the experience of one center.
Pancreatic cancer is a malignant tumor originating from the pancreatic epithelium. Despite constant efforts and intensive research, it has not yet been possible to identify risk factors that significantly affect the early diagnosis and effectiveness of pancreatic cancer treatment. In the Russian Federation in 2021, 15055 patients with pancreatic cancer were identified, of which stage III -16.9%, stage IV -58.2%. Mortality in the first year of life from the moment of diagnosis was 65.1%. A total of 1,856 patients underwent radical surgical treatment. Features of the clinical picture of prostate cancer a long latent course and similarity with the clinic of chronic pancreatitis can cause late diagnosis of the disease. In about 70% of cases, the disease is manifested by the syndrome of mechanical jaundice, which requires additional invasive methods of diagnosis and treatment. At the time of diagnosis verification, 80-85% of patients are already inoperable due to local or remote spread of the tumor process. The average life expectancy of patients with unresectable pancreatic cancer is about 6-7 months. After radical surgical treatment, the 5-year survival rate of patients with this pathology, according to the results of various authors, ranges from 0 to 30%.
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