埃及蜂毒制剂对兔子免疫反应的研究

Abir Elfiky, Eman Abououf
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引用次数: 0

摘要

免疫系统反复接触作为抗原的蜂毒,会导致免疫反应显著增强。本研究尝试了不同的免疫学方案,通过使用蜂毒的水溶液或乳化制剂来达到最大的免疫效果和最小的过敏副作用。研究使用了三组雄性兔子,每组一岁,为期四周。在注射蜂毒前和感染蜂毒后每周对兔子进行一次血液采样,以测定 IgG 和 IgE。结果表明,注射埃及蜂毒水剂能够提高免疫反应水平,而不会产生明显的过敏反应。
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INVESTIGATION OF IMMUNOLOGICAL RESPONSE OF EGYPTIAN BEE VENOM PREPARATION IN RABBITS
The repeated exposure of the immune system to bee venom as antigen leads to significant increase in immune response. In this study different immunological schedules were tried to reach maximum immunological effect with the least allergic side effect either by using and aqueous or emulsified preparation of bee venom. Three groups of male rabbits of one year old each were used for a period of four weeks. The blood samples were with drown before bee venom injection and weekly after its infection for determination of IgG and IgE. The results showed that injection of Egyptian bee venom in an aqueous form have the ability to boost the level of immune response without significant allergic reaction.
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