儿科病房 0-36 个月大的下呼吸道感染患儿与同龄健康儿童维生素 A 和维生素 D 水平的比较

Harun Çatak, Abdulrahman Özel, Övgü Büke, Özlem Bostan Gayret, Meltem Erol
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Materials and Method The study included 82 children who applied to pediatric outpatient clinic between February 1st 2020 and June 30th 2020 with lower respiratory tract infection between the age 0-36 months, who gave blood sample for determination of serum vitamin A and vitamin D levels. 58 healthy children who applied to the outpatient clinic for routine check-up were determined as the control group. Age, sex, height and weight of all children were recorded. Results The average vitamin D level of those in the lower respiratory tract infection group was found to be 15.96±7.49ng/ml and those in the healthy group had average vitamin D levels of 32.19±14.27 ng/ml, showing that the sick group had statistically significantly lower levels of vitamin D (p=0.0001). The average vitamin A level of those in the sick group was found to be 170.42±60.42 ng/ml, whereas those in the control group had average vitamin A levels of 284.42±71.2 ng/ml, which showed that those in the sick group had statistically significantly low levels of vitamin A (p=0.0001). Our study showed that there is a positive statistically meaningful correlation between the vitamin D variable and the vitamin A variable (r=0.432, p=0.0001). Conclusions Our study is the only study in the literature comparing both the vitamin A and vitamin D levels of patients with lower respiratory tract infection. 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引用次数: 0

摘要

背景下呼吸系统感染在幼儿中非常常见,可能需要住院治疗。我们的研究旨在通过比较 0-36 个月的下呼吸道感染患者和健康儿童的血清维生素 A 和维生素 D 水平,确定这些维生素的缺乏是否是导致下呼吸道感染的危险因素。 材料与方法 本研究纳入了 2020 年 2 月 1 日至 2020 年 6 月 30 日期间到儿科门诊就诊的 82 名 0-36 个月大的下呼吸道感染患儿,他们都提供了血样以测定血清维生素 A 和维生素 D 水平。58 名到门诊进行常规检查的健康儿童作为对照组。记录所有儿童的年龄、性别、身高和体重。 结果 发现下呼吸道感染组的平均维生素 D 水平为(15.96±7.49)ng/ml,健康组的平均维生素 D 水平为(32.19±14.27)ng/ml,表明患病组的维生素 D 水平显著低于健康组(P=0.0001)。研究发现,患病组的维生素 A 平均水平为(170.42±60.42)纳克/毫升,而对照组的维生素 A 平均水平为(284.42±71.2)纳克/毫升,这表明患病组的维生素 A 水平在统计学上明显偏低(P=0.0001)。我们的研究表明,维生素 D 变量与维生素 A 变量之间存在统计学意义上的正相关(r=0.432,p=0.0001)。 结论 我们的研究是文献中唯一一项比较下呼吸道感染患者维生素 A 和维生素 D 水平的研究。与健康儿童相比,下呼吸道感染患者的维生素 A 和维生素 D 水平较低,因此我们预测,控制此类患者的维生素水平并在必要时给予适当治疗,将降低下呼吸道感染的发病率和死亡率。
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Çocuk Servisinde Yatırılarak Tedavi Edilen Alt Solunum Yolu Enfeksiyonu Tanılı 0 – 36 Ay Arası Çocukların Vitamin A Ve Vitamin D Düzeylerinin Aynı Yaş Grubu Sağlıklı Çocuklar Ile Karşılaştırılması
Background Lower respiratory system infections are highly common in young children and may require inpatient treatment. Studies have shown that patients treated and followed up for lower respiratory system infections have low levels of vitamin A and Vitamin D. In our study, we aimed to determine whether the deficiencies of these vitamins are risk factors for the development of lower respiratory system infections by comparing the serum vitamin A and vitamin D levels of patients 0-36months with lower respiratory tract infection and healthy children. Materials and Method The study included 82 children who applied to pediatric outpatient clinic between February 1st 2020 and June 30th 2020 with lower respiratory tract infection between the age 0-36 months, who gave blood sample for determination of serum vitamin A and vitamin D levels. 58 healthy children who applied to the outpatient clinic for routine check-up were determined as the control group. Age, sex, height and weight of all children were recorded. Results The average vitamin D level of those in the lower respiratory tract infection group was found to be 15.96±7.49ng/ml and those in the healthy group had average vitamin D levels of 32.19±14.27 ng/ml, showing that the sick group had statistically significantly lower levels of vitamin D (p=0.0001). The average vitamin A level of those in the sick group was found to be 170.42±60.42 ng/ml, whereas those in the control group had average vitamin A levels of 284.42±71.2 ng/ml, which showed that those in the sick group had statistically significantly low levels of vitamin A (p=0.0001). Our study showed that there is a positive statistically meaningful correlation between the vitamin D variable and the vitamin A variable (r=0.432, p=0.0001). Conclusions Our study is the only study in the literature comparing both the vitamin A and vitamin D levels of patients with lower respiratory tract infection. Vitamin A and vitamin D levels of patients with lower respiratory tract infections are found to be lower compared to healthy children, therefore we predict that controlling the vitamin levels of such patient and giving the appropriate treatment when needed, will lower the morbidity and mortality caused by lower respiratory tract infections.
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