精子畸形指数在经历过和未经历过 covid-19 的患者之间的比较

Deniz AKA SATAR, Ridvan Bagci, Umut Demi̇rdelen
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摘要

目的:自 2019 年 12 月发现新型冠状病毒 SARS-CoV-2 以来,该病毒在全球迅速传播,引发了 COVID-19(冠状病毒病-19)大流行。男性生殖系统易受 COVID-19 的影响,导致精液参数的潜在改变。在本研究中,我们对曾感染过 COVID-19 和未感染过 COVID-19 的患者进行了比较,特别是将精子畸形指数(SDI)作为评估精子形态的参数。材料与方法研究对象包括在 2022 年 11 月 29 日至 2022 年 12 月 29 日期间向医院 Andrology 实验室提出申请的 134 名 18 岁以上患者。其中,44 名患者接受过 COVID-19 治疗,90 名患者未接受过 COVID-19 治疗。这些患者的 SDI 参数与其他精液参数(射精量、精子浓度、精子总数、总活力、渐进活力和正常形态精子百分比)进行了比较。SDI 的计算方法是将观察到的畸形总数除以精子总数。结果两组的 SDI 值有显著差异,差异有统计学意义(P0.05)。结论作为精液参数之一的 SDI 值在两组中均有显著差异。有必要开展进一步的综合研究,以深入探讨 COVID-19 对精液参数的影响。
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COMPARISON OF SPERM DEFORMITY INDEXES BETWEEN PATIENTS WHO HAVE AND HAVE NOT EXPERIENCED COVID-19
Objective: Ever since its identification in December 2019, the novel coronavirus SARS-CoV-2 has rapidly disseminated worldwide, giving rise to the COVID-19 (coronavirus disease-19) pandemic. The male reproductive system is susceptible to the effects of COVID-19, leading to potential alterations in semen parameters. In this study, we conducted a comparison between patients who have previously contracted COVID-19 and those who have not, specifically focusing on the sperm deformity index (SDI) as a parameter for assessing sperm morphology. Material and Method: 134 patients over the age of 18 who applied to Hospital Andrology Laboratory between 29 November 2022 and 29 December 2022 were included in the study. Of these, 44 were patients who have had COVID-19, and 90 were patients who have not had COVID-19. These patients were compared in terms of SDI parameter and other semen parameters (ejaculate volume, sperm concentration, total sperm count, total motility, progressive motility and percentage of normal morphology sperm). The calculation of the SDI was performed by dividing the total number of observed deformities by the total count of sperm. Results: A noteworthy distinction was observed in the SDI values between the two groups, with a statistically significant difference (p0.05). Conclusion: SDI, one of the semen parameters, was found to be significantly different in both groups. Further comprehensive studies are warranted to thoroughly investigate the impact of COVID-19 on semen parameters.
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