{"title":"不同哌嗪类似物的神经药理潜力:最近的一项前瞻性研究","authors":"Mamdouh Allahyani, Mazen Almehmadi, Ahad Amer Alsaiari, Mohammad Asif, Sachin Kumar","doi":"10.2174/0118756298277743231213065544","DOIUrl":null,"url":null,"abstract":": Heterocyclic moiety is a key part of some enzymes and vitamins and plays a vital role in various biochemical and enzymatic processes. Piperazine ring is a heterocyclic moiety present in various well-known drugs and is effective against different types of diseases by acting on a variety of receptors. Various piperazine analogs possess diverse biological activities, especially in central nervous system disorders, which involve the activation of neurotransmitter receptors and targeting various enzymes and act as antianxiety, antipsychotic, antidepressant, etc. This review is focused on the piperazine derivatives and their diverse therapeutic potential against different types of diseases particularly against neuronal disorders.","PeriodicalId":18632,"journal":{"name":"Mini-reviews in Organic Chemistry","volume":"23 1","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Neuropharmacological Potential of Different Piperazine Analogs: A Recent Prospective\",\"authors\":\"Mamdouh Allahyani, Mazen Almehmadi, Ahad Amer Alsaiari, Mohammad Asif, Sachin Kumar\",\"doi\":\"10.2174/0118756298277743231213065544\",\"DOIUrl\":null,\"url\":null,\"abstract\":\": Heterocyclic moiety is a key part of some enzymes and vitamins and plays a vital role in various biochemical and enzymatic processes. Piperazine ring is a heterocyclic moiety present in various well-known drugs and is effective against different types of diseases by acting on a variety of receptors. Various piperazine analogs possess diverse biological activities, especially in central nervous system disorders, which involve the activation of neurotransmitter receptors and targeting various enzymes and act as antianxiety, antipsychotic, antidepressant, etc. This review is focused on the piperazine derivatives and their diverse therapeutic potential against different types of diseases particularly against neuronal disorders.\",\"PeriodicalId\":18632,\"journal\":{\"name\":\"Mini-reviews in Organic Chemistry\",\"volume\":\"23 1\",\"pages\":\"\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-02-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mini-reviews in Organic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.2174/0118756298277743231213065544\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mini-reviews in Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.2174/0118756298277743231213065544","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Neuropharmacological Potential of Different Piperazine Analogs: A Recent Prospective
: Heterocyclic moiety is a key part of some enzymes and vitamins and plays a vital role in various biochemical and enzymatic processes. Piperazine ring is a heterocyclic moiety present in various well-known drugs and is effective against different types of diseases by acting on a variety of receptors. Various piperazine analogs possess diverse biological activities, especially in central nervous system disorders, which involve the activation of neurotransmitter receptors and targeting various enzymes and act as antianxiety, antipsychotic, antidepressant, etc. This review is focused on the piperazine derivatives and their diverse therapeutic potential against different types of diseases particularly against neuronal disorders.
期刊介绍:
Mini-Reviews in Organic Chemistry is a peer reviewed journal which publishes original reviews on all areas of organic chemistry including organic synthesis, bioorganic and medicinal chemistry, natural product chemistry, molecular recognition, and physical organic chemistry. The emphasis will be on publishing quality papers very rapidly, without any charges.
The journal encourages submission of reviews on emerging fields of organic chemistry including:
Bioorganic Chemistry
Carbohydrate Chemistry
Chemical Biology
Chemical Process Research
Computational Organic Chemistry
Development of Synthetic Methodologies
Functional Organic Materials
Heterocyclic Chemistry
Macromolecular Chemistry
Natural Products Isolation And Synthesis
New Synthetic Methodology
Organic Reactions
Organocatalysis
Organometallic Chemistry
Theoretical Organic Chemistry
Polymer Chemistry
Stereochemistry
Structural Investigations
Supramolecular Chemistry