在环境研究中估计因果效应时可能出现的偏差类型以及如何解释这些偏差

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-02-07 DOI:10.1186/s13750-024-00324-7
Ko Konno, James Gibbons, Ruth Lewis, Andrew S Pullin
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引用次数: 0

摘要

为了给环境政策和实践提供信息,研究人员通过开展初级研究(如影响评估)或二级研究(如证据审查)来估计干预/暴露的效果。如果这些估计值来自于开展/报告不力的研究,那么它们可能会提供有偏差的估计值,从而误导政策和实践。人们已经描述了许多类型的偏差,尤其是在健康和医学科学领域。我们的目标是从文献中找出与环境领域因果效应估算相关的所有偏差类型。通过使用偏差目录 (catalogofbias.org),并查阅以前整理和描述过偏差的主要出版物(n = 11),我们初步确定了所有类型的偏差。我们确定了 121 种(共 206 种)与环境领域因果效应估算相关的偏差类型。我们对每种相关的偏差类型都进行了一般性解释,这些偏差类型涵盖了初级研究的七个偏差风险领域:混杂偏差风险;干预后/暴露选择偏差风险;误分类/误测量对比偏差风险;绩效偏差风险;检测偏差风险;结果报告偏差风险;结果评估偏差风险,以及次级研究的四个领域:搜索偏差风险;筛选偏差风险;研究评估和数据编码/提取偏差风险;数据综合偏差风险。我们的整理工作应有助于环境领域的科学家和决策者更好地认识因果效应估算偏差的性质。未来的研究需要对整理出的偏差类型进行正式定义,例如通过数学公式进行分解。
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Potential types of bias when estimating causal effects in environmental research and how to interpret them
To inform environmental policy and practice, researchers estimate effects of interventions/exposures by conducting primary research (e.g., impact evaluations) or secondary research (e.g., evidence reviews). If these estimates are derived from poorly conducted/reported research, then they could misinform policy and practice by providing biased estimates. Many types of bias have been described, especially in health and medical sciences. We aimed to map all types of bias from the literature that are relevant to estimating causal effects in the environmental sector. All the types of bias were initially identified by using the Catalogue of Bias (catalogofbias.org) and reviewing key publications (n = 11) that previously collated and described biases. We identified 121 (out of 206) types of bias that were relevant to estimating causal effects in the environmental sector. We provide a general interpretation of every relevant type of bias covered by seven risk-of-bias domains for primary research: risk of confounding biases; risk of post-intervention/exposure selection biases; risk of misclassified/mismeasured comparison biases; risk of performance biases; risk of detection biases; risk of outcome reporting biases; risk of outcome assessment biases, and four domains for secondary research: risk of searching biases; risk of screening biases; risk of study appraisal and data coding/extraction biases; risk of data synthesis biases. Our collation should help scientists and decision makers in the environmental sector be better aware of the nature of bias in estimation of causal effects. Future research is needed to formalise the definitions of the collated types of bias such as through decomposition using mathematical formulae.
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CiteScore
7.20
自引率
4.30%
发文量
567
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