素食诱发一名有遗传倾向的中年男性新发急性痛风性关节炎:罕见病例

Poonam Agrawal, Mohit Agrawal, Deepti Chopra
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引用次数: 0

摘要

痛风是一种代谢性疾病,其特征是由于尿酸单钠(MSU)结晶在关节和软组织中沉积而引起的急性或慢性关节炎。我们接诊了一例 45 岁非糖尿病、非酒精中毒、非吸烟的男性患者,主诉右手和左腿疼痛并伴有关节活动受限,且疼痛已持续 14 小时。患者提供的病史显示,在出现这些症状之前,他曾连续两天食用花椰菜、蘑菇、豆类和含糖碳酸饮料。据我们所知,这是文献中报道的首例因食用富含嘌呤的素食而诱发痛风的病例。本病例报告强调,有痛风遗传倾向的人在食用富含嘌呤的饮食(如红肉、海鲜、菜花、菠菜、rabjma、孟加拉草、蘑菇、含果糖的软饮料)时需要特别小心。
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Vegetarian diet induced new onset acute gouty arthritis in a middle-aged genetically predisposed male: A rare presentation
Gout is a metabolic disease characterised by acute or chronic arthritis which is due to deposition of Monosodium urate (MSU) crystals in joints and soft tissues. Classically described as a disease associated with hyperuricemia which may be due to metabolic defect in uric acid production or due to impaired renal excretion.We present a case of 45 year old nondiabetic, non-alcoholic, non-smoker male presented to orthopaedic OPD with complain of pain in right hand and left leg with restriction of joint mobility for past 14 hours.On carefully eliciting the dietary history patient revealed that he was a vegetarian and was on high purine rich diet for past 2 weeks due to family functions and various gatherings. Patient gave the history of consumption of cauliflower, mushrooms, beans along with sweetened carbonated drinks on two consecutive days before the onset of these symptoms.Serum uric acid 4.5 mg/dl, C-reactive protein was 9 mg/dl. To best of our knowledge this is the first case being reported in literatures where purine rich vegetarian diet has induced new case of gout.This kind of gout precipitation after consuming vegetarian diet is rarely reported in literature. This case report emphasizes upon the need of special caution to be taken by persons who are genetically predisposed to gout, while consuming purine rich diet like red meat, seafood, cauliflowers, spinach, rajma, Bengal gram, mushrooms, soft drinks sweetened with fructose.
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