接受二尖瓣手术治疗无症状疾病患者的疗效和生活质量

Amit Iyengar MD, MSE , Noah Weingarten MD , David Rekhtman BS , Cindy Song BA , Max Shin BS , Mark R. Helmers MD , John Kelly MD , Pavan Atluri MD
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摘要

方法对 2010 年至 2019 年期间接受二尖瓣手术的成人进行回顾性研究。如果经转诊心脏病专家和外科医生会诊后认为患者无症状,则将其纳入调查范围。对患者进行了电话调查,调查内容包括堪萨斯城心肌病问卷以及对手术满意度的自由回答。结果包括存活率、堪萨斯城心肌病问卷指标以及自由回答问题的主题分析。他们的平均年龄为 60.3 ± 12.1 岁,71% 为男性。没有患者患有心内膜炎,34%的患者射血分数下降(60%)。95%的患者实现了修复。住院时间中位数为6(5-8)天。十年存活率为 91%,射血分数无差异。堪萨斯城心肌病问卷综合评分为 100 分(96-100 分)。得分最低的部分是 "生活质量",22%的患者表示对目前的心脏状况 "基本满意"。最常见的主题是对手术结果的感激之情(58%)、对能够保持运动的满意度(23%)以及对早期疾病治疗的喜悦感(21%)。只有一名患者(0.7%)对手术选择表示遗憾。结论对无症状疾病进行前庭成形术可为特定患者带来良好的长期疗效,大多数患者的生活质量极佳,并对目前的健康状况感到满意。随着适应症的增加,继续评估生活质量对于评估二尖瓣手术的效果非常重要。
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Outcomes and quality of life in patients receiving mitral surgery for asymptomatic disease

Objectives

We sought to characterize the demographics, outcomes, and quality of life of asymptomatic patients undergoing mitral valve surgery at our center over a 10-year period.

Methods

Adults undergoing mitral surgery were retrospectively reviewed between 2010 and 2019. Patients were included if deemed asymptomatic by review of referring cardiologist and surgeon consultation. Patients were administered a telephone survey consisting of the Kansas City Cardiomyopathy Questionnaire as well as free-response regarding satisfaction surrounding their operation. Outcomes included survival, Kansas City Cardiomyopathy Questionnaire metrics, and thematic analysis of free response questions.

Results

A total of 145 patients were identified who were deemed asymptomatic. Their average age was 60.3 ± 12.1 years, and 71% were male. No patients had endocarditis, and 34% had decreased ejection fraction (<60%). Repair was achieved in 95% of patients. Median length of stay was 6 (5-8) days. Ten-year survival was 91%, with no differences noted by ejection fraction. Composite Kansas City Cardiomyopathy Questionnaire score was 100 (96-100). The lowest component score was “Quality of Life,” with 22% of patients reporting being “mostly satisfied” with present cardiac status. Most common themes expressed were gratitude with surgery results (58%), satisfaction with being able to stay active (23%), and happiness with early disease treatment (21%). Only 1 patient (0.7%) expressed regret with surgery choice.

Conclusions

Mitral surgery for asymptomatic disease can be performed with good long-term outcomes in select patients, and the majority experience excellent quality of life and satisfaction with current health. Continued assessments of quality of life are important in evaluating outcomes of mitral surgery as indications grow.

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