利用基于磁性纳米颗粒的磁性无线传感器实时监测呼气生物标记物

IF 5.4 Q1 CHEMISTRY, ANALYTICAL Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI:10.1016/j.sbsr.2024.100629
J.D. Aguilera , D. Arranz , A. Peña , P. Marín , M.C. Horrillo , P. de la Presa , D. Matatagui
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引用次数: 0

摘要

本文提出了一种具有气体遥感能力的创新装置,该装置基于磁性纳米粒子与呼出气体生物标记物之间的相互作用,这些生物标记物可能与新陈代谢有关。研究使用了 30 纳米左右的磁铁矿(Fe₃O₄)纳米粒子。表面吸附的气体分子会调制纳米粒子的磁化,在钇铁石榴石(YIG)薄膜上传播的磁静态表面自旋波(MSSW)可通过诱导频移来检测这种调制。通过对磁性模型的模拟,对远程气体传感器进行了优化。模拟结果表明,通过将纳米结构封装在聚四氟乙烯(PTFE)管中并检测其磁化率的百万分之一变化,开发高性能远程传感器是可行的。研究结果表明,利用自旋波作为感应器,可以开发出新型、廉价、可重复使用的非接触式磁性气体传感器。所开发的传感器对浓度低至 50 ppm 的不同呼气生物标记物具有很高的灵敏度和选择性。
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Real-time monitoring of breath biomarkers using magnonic wireless sensor based on magnetic nanoparticles

In this paper, an innovative device with gas remote-sensing capability is proposed, which is based on the interaction between magnetic nanoparticles and gases associated with exhaled breath biomarkers that can have a metabolic origin. Magnetite (Fe₃O₄) nanoparticles of around 30 nm have been used. The gas molecules adsorbed on surface modulate the magnetization of the nanoparticles and magnetostatic surface spin waves (MSSW) propagated on an yttrium iron garnet (YIG) thin film are used to detect this modulation by the induced frequency shift. The optimization of the remote gas sensor has been carried out through simulations of a magnetic model. Simulations show the feasibility of developing a high-performance remote sensor by encapsulating the nanostructures in a polytetrafluoroethylene (PTFE) tube and detecting part per million changes in their magnetization. The results show the possibility of developing new, inexpensive, reusable, contactless magnetic gas sensors employing spin waves as transductor. The developed sensor shows a high sensitivity and selectivity to concentrations as low as 50 ppm of different breath biomarkers.

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来源期刊
Sensing and Bio-Sensing Research
Sensing and Bio-Sensing Research Engineering-Electrical and Electronic Engineering
CiteScore
10.70
自引率
3.80%
发文量
68
审稿时长
87 days
期刊介绍: Sensing and Bio-Sensing Research is an open access journal dedicated to the research, design, development, and application of bio-sensing and sensing technologies. The editors will accept research papers, reviews, field trials, and validation studies that are of significant relevance. These submissions should describe new concepts, enhance understanding of the field, or offer insights into the practical application, manufacturing, and commercialization of bio-sensing and sensing technologies. The journal covers a wide range of topics, including sensing principles and mechanisms, new materials development for transducers and recognition components, fabrication technology, and various types of sensors such as optical, electrochemical, mass-sensitive, gas, biosensors, and more. It also includes environmental, process control, and biomedical applications, signal processing, chemometrics, optoelectronic, mechanical, thermal, and magnetic sensors, as well as interface electronics. Additionally, it covers sensor systems and applications, µTAS (Micro Total Analysis Systems), development of solid-state devices for transducing physical signals, and analytical devices incorporating biological materials.
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