髋部骨折患者即时筛查后的静脉血栓栓塞症患病率。

Yoon-Vin Kim, Joo-Hyoun Song, Young-Wook Lim, Woo-Lam Jo, Seung-Hun Ha, Kee-Haeng Lee
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引用次数: 0

摘要

目的:静脉血栓栓塞症(VTE)是髋部骨折患者的主要并发症,可能在术前就存在。材料和方法:D-二聚体水平升高的髋部骨折患者使用计算机断层扫描(CT)血管造影术进行 VTE 筛查。术前对确诊为 VTE 的患者进行抗凝治疗,术后再进行抗凝治疗。对病历进行审查,以确定术前 VTE 的风险因素,并确定患者的预后:在 524 名髋部骨折患者中,有 66 名患者(12.6%)被确诊为 VTE,包括 42 名深静脉血栓形成(DVT)患者、17 名肺血栓栓塞(PTE)患者和 7 名同时患有 DVT 和 PTE 的患者。在 VTE 患者中,68.2% 是在受伤后 24 小时内确诊的,其中 33.3% 患有 PTE。与无 VTE 患者相比,VTE 患者有超重倾向(PP=0.02)。股骨干骨折患者(几率比 [OR] 4.83,95% 置信区间 [CI] 2.18-10.69)和超重患者(OR 2.12,95% CI 1.17-3.85)发生 VTE 的风险较高,而之前服用过抗凝剂的患者发生 VTE 的风险较低(OR 0.36,95% CI 0.18-0.74)。术前诊断为 VTE 的患者在手术前后均无症状:临床医生应意识到在受伤后 24 小时内可能会出现 VTE,因此应考虑对高危患者进行 VTE 筛查或采取预防措施。
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Prevalence of Venous Thromboembolism after Immediate Screening in Hip Fracture Patients.

Purpose: Venous thromboembolism (VTE) is a major complication for hip fracture patients, and may exist preoperatively. This study aimed to examine the prevalence of VTE after immediate screening in hip fracture patients.

Materials and methods: Hip fracture patients with an elevated level of D-dimer underwent screening for VTE using computed tomography (CT) angiography. Anticoagulation treatments were administered preoperatively to patients diagnosed with VTE, followed by administration of additional anticoagulation postoperatively. Medical records were reviewed to identify risk factors for preoperative VTE and determine the prognosis of the patients.

Results: Among 524 hip fracture patients, 66 patients (12.6%) were diagnosed with VTE, including 42 patients with deep vein thrombosis (DVT), 17 patients with pulmonary thromboembolism (PTE), and 7 patients with both DVT and PTE. Of the patients with VTE, 68.2% were diagnosed within 24 hours of injury, and 33.3% of these patients had PTE. VTE patients showed a tendency toward being overweight (P<0.01) and not on anticoagulant medication (P=0.02) compared to patients without VTE. The risk of VTE was higher for femur shaft fractures (odds ratio [OR] 4.83, 95% confidence interval [CI] 2.18-10.69) and overweight patients (OR 2.12, 95% CI 1.17-3.85), and lower for patients who were previously on anticoagulants (OR 0.36, 95% CI 0.18-0.74). Patients with preoperatively diagnosed VTE were asymptomatic before and after surgery.

Conclusion: Clinicians should be aware that VTE may be present within 24 hours of injury, and screening for VTE or prophylactic measures should be considered for high-risk patients.

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