对美国药物检测颠覆策略的系统性网络监测。

IF 2.6 3区 医学 Q2 BIOCHEMICAL RESEARCH METHODS Drug Testing and Analysis Pub Date : 2025-01-01 Epub Date: 2024-03-23 DOI:10.1002/dta.3671
Megan Grabenauer, Svante Vikingsson, Richard A Olson, Faith E Lyons, Lisa S Davis, Eugene D Hayes, Ronald R Flegel
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引用次数: 0

摘要

由于药检呈阴性往往是就业的一个条件,一些吸毒者会试图颠覆药检。在本研究中,我们利用系统性的网络监测来调查网上是如何讨论颠覆药物测试的。我们从公共网站和暗网(n = 634,2021 年 7 月至 12 月)获取了与药检颠覆相关的帖子。来自公共网站的大部分信息来自 Twitter(65%),94% 的暗网帖子来自 Reddit。这些帖子都经过人工编码,以提取有关药物测试颠覆策略的定量和定性信息。大多数帖子讨论了尿液药物检测(85%),其次是毛发(11%)和口服液(2%),讨论最多的药物是大麻(72%)和可卡因(7.3%)。尿液药物检测颠覆主要涉及标本替代,使用合成尿液或他人尿液。另一种策略是通过摄入肌酸来掩盖稀释的尿液。尿液掺假很少被讨论。破坏毛发检测涉及使用漂白剂、小苏打和/或洗涤剂等产品进行粗暴处理。此外,还讨论了脱毛问题。口腔液检测颠覆主要是通过用力刷牙和刷舌,以及使用漱口水、双氧水、口香糖和商业解毒产品来清除口腔中的毒品。本研究强调了捐献者使用的颠覆策略。虽然这些策略的有效性证据很少,但这些信息可能有助于指导未来的研究和样本有效性测试的发展,以最大限度地减少药物测试颠覆企图的影响。
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Systematic web monitoring of drug test subversion strategies in the United States.

As negative drug tests are frequently a condition for employment, some people who use drugs will try to subvert the testing. In this study, systematic web monitoring was used to investigate how drug test subversion is discussed online. Posts pertaining to drug test subversion were obtained from public websites and the dark web (n = 634, July-December 2021). Most information from public websites came from Twitter (65%), and 94% of dark web posts were from Reddit. The posts were manually coded to extract quantitative and qualitative information about drug test subversion tactics. Most posts discussed urine drug tests (85%), followed by hair (11%) and oral fluid (2%), and the most discussed drugs were marijuana (72%) and cocaine (7.3%). Urine drug test subversion mainly pertained to specimen substitution, with synthetic urine or urine from another person. Another strategy was to mask diluted urine by ingesting creatine. Urine adulteration was rarely discussed. Hair test subversion involved harsh treatments with products such as bleach, baking soda, and/or detergent. Hair removal was also discussed. Oral fluid test subversion focused on removing drugs from the oral cavity through vigorous brushing of teeth and tongue as well as the use of mouthwash, hydrogen peroxide, gum, and commercial detox products. This study highlights subversion strategies used by donors. Although little evidence was provided as to the effectiveness of these strategies, this information may help guide future studies and development of specimen validity testing to minimize the impact of drug test subversion attempts.

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来源期刊
Drug Testing and Analysis
Drug Testing and Analysis BIOCHEMICAL RESEARCH METHODS-CHEMISTRY, ANALYTICAL
CiteScore
5.90
自引率
24.10%
发文量
191
审稿时长
2.3 months
期刊介绍: As the incidence of drugs escalates in 21st century living, their detection and analysis have become increasingly important. Sport, the workplace, crime investigation, homeland security, the pharmaceutical industry and the environment are just some of the high profile arenas in which analytical testing has provided an important investigative tool for uncovering the presence of extraneous substances. In addition to the usual publishing fare of primary research articles, case reports and letters, Drug Testing and Analysis offers a unique combination of; ‘How to’ material such as ‘Tutorials’ and ‘Reviews’, Speculative pieces (‘Commentaries’ and ‘Perspectives'', providing a broader scientific and social context to the aspects of analytical testing), ‘Annual banned substance reviews’ (delivering a critical evaluation of the methods used in the characterization of established and newly outlawed compounds). Rather than focus on the application of a single technique, Drug Testing and Analysis employs a unique multidisciplinary approach to the field of controversial compound determination. Papers discussing chromatography, mass spectrometry, immunological approaches, 1D/2D gel electrophoresis, to name just a few select methods, are welcomed where their application is related to any of the six key topics listed below.
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