利用石墨炉原子吸收光谱法测定和评估放射工作人员血液中的微量元素

Ahmed Jaber Ibrahim
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摘要

本研究旨在通过 GF-AAS 分析法评估伊拉克医学放射摄影工作者血液中微量元素的潜在毒性影响。这项研究涉及 50 名来自伊拉克 Thi-Qar 市 Al-Shatrah 综合医院医学影像领域的男性血液放射摄影工作者。所有工人的年龄都在 35-50 岁之间,工作时间不到 10 年。研究将这些工人与 50 名健康男性进行了比较。研究发现,与健康对照组相比,放射工作人员体内铜、铅、镉和钙的含量明显增加,而锌和硒的含量则明显下降。此外,还通过接收器工作特征曲线(ROC)估算了特异性和置信区间(95%)。这项研究提供了确凿的证据,证明放射工作人员血液中的微量元素水平出现了紊乱,使他们更容易因暴露于辐射而患上多种疾病,这预示着需要采取更多的辐射预防措施。用 DW 稀释样本至 20(n=10,RSD< 5%)后,采用 GF-AAS 方法测定人体血清中的镉、铜、锌、硒和铅,其线性范围分别为 0.2-6.0 µg dL-1、6.0-200 µg dL-1、8.0-200 µg dL-1、10-250 µg dL-1、4-120 µg dL-1。
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the Determination and evaluation of trace elements in the blood of radiography workers using graphite furnace atomic absorption spectrometry
This study aimed to evaluate the potentially toxic effects of trace elements in the blood of Iraqi medical radiography workers by analyzing them through GF-AAS. The study involved 50 male blood radiography workers from the medical imaging field at Al-Shatrah General Hospital in Thi-Qar City, Iraq. All workers were aged between 35-50 years and had worked for less than 10 years. The study compared these workers with 50 healthy men. The study found a significant increase in the levels of Cu, Pb, Cd, and Ca among radiography workers compared to the healthy control group, while Zn and Se levels decreased significantly. Moreover, Specificity and confidence interval (95%) were estimated via the receiver operating characteristic curve (ROC). The study provided conclusive evidence of disturbances in the levels of trace elements in the blood of radiographer workers, which makes them more susceptible to many diseases because of their radiation exposure. which portends the more preventive measures of radiation. The linear range of Cd, Cu, Zn, Se and Pb in human serum were obtained 0.2-6.0 µg dL-1, 6.0-200 µg dL-1, 8.0-200 µg dL-1, 10-250 µg dL-1, 4-120 µg dL-1 by GF-AAS after dilution samples with DW up to 20 (n=10, RSD< 5%).
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