Nazia Khan, Md Irfanul Haque, Shailesh Shenoy, Rahul Puthenkandathil, Preeti Kale
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引用次数: 0
摘要
在聚合酶链式反应(PCR)等技术进步的推动下,分子牙科已成为牙科研究和实践中前景广阔的前沿领域。聚合酶链式反应能够精确灵敏地检测各种口腔病原体、与牙科疾病相关的遗传标记以及宿主反应因子,从而彻底改变了牙科领域。它能从最少的起始材料中扩增出特定的 DNA 序列,从而有助于快速准确地诊断牙科感染、牙周疾病和口腔疾病的遗传倾向。此外,基于 PCR 的方法还增进了我们对口腔微生物组组成及其与整体健康关系的了解。这篇综述文章旨在通过概述 PCR 的应用、当前发展和未来前景,阐明 PCR 在分子牙科中的变革性作用。
Molecular dentistry: Polymerase chain reaction’s transformative role
Molecular dentistry, propelled by advancements in techniques such as Polymerase Chain Reaction (PCR), has emerged as a promising frontier in dental research and practice. PCR has revolutionized the field of dentistry by enabling precise and sensitive detection of various oral pathogens, genetic markers associated with dental diseases, and host response factors. Its ability to amplify specific DNA sequences from minimal starting material has facilitated rapid and accurate diagnosis of dental infections, periodontal diseases, and genetic predispositions to oral conditions. Moreover, PCR-based methods have enhanced our understanding of the oral microbiome composition and its relationship with overall health. This review article aims to elucidate the transformative role of PCR in molecular dentistry by providing an overview of its applications, current developments, and future prospects.