先期镇痛对腺样体扁桃体切除术和扁桃体切除术恢复期谵妄的影响

Bilge OLGUN KELES, Elvan TEKİR YILMAZ
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摘要

摘要 目的:急诊谵妄是一种病因不明的现象,多见于幼儿,以攻击性行为、缺乏目光接触和对环境缺乏感知为特征。它的病因很多,但头颈部手术、吸入性药物和术后疼痛是最常见的原因。PAED 量表是最敏感的量表,10 分或以上表示立即出现谵妄。预先镇痛是指在疼痛刺激发生之前中断疼痛通路,其在术后镇痛中的有效性已被许多研究证实。本研究的设计假设是,通过抢先镇痛减轻术后疼痛将减少急诊谵妄。材料和方法:经伦理委员会批准后,96 名年龄在 2-7 岁、接受腺扁桃体切除术和扁桃体切除术的 ASAI-II 级患者被随机分为两组。预先镇痛组在诱导前使用镇痛剂,术中镇痛组在手术开始后 15 分钟使用镇痛剂。在恢复室中,使用 PAED 量表评估 ED,使用 FLACC 评分评估疼痛评分。PAED>10为恢复期谵妄。主要结果是恢复期谵妄的发生率。次要结果为谵妄和疼痛评分。结果抢救组的 PAED 和 FLACC 评分明显较低。两组的 ED 发生率仅在 5 分钟时有明显差异。结论在接受腺扁桃体切除术和扁桃体切除术的儿童中,抢先镇痛可降低术后疼痛评分和谵妄评分,但不能降低恢复期谵妄的发生率。
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Adenotonsillektomi ve Tonsillektomi operasyonlarında preemptif analjezinin derlenme deliryumu üzerine etkisi
ABSTRACT Objective: Emergency delirium is a phenomenon of unknown etiology, mostly seen in young children, characterised by aggressive behaviour, lack of eye contact and lack of awareness of the environment. It has been shown to have many causes, but head and neck surgery, inhaled agents and post-operative pain are the most common. The PAED scale is the most sensitive scale and a score of 10 or more indicates immediate delirium. Pre-emptive analgesia is the interruption of pain pathways before the painful stimulus occurs, and its effectiveness in post-operative analgesia has been confirmed by many studies. This study was designed with the hypothesis that post-operative pain reduced by pre-emptive analgesia would reduce emergency delirium. Materials and methods: After ethics committee approval, 96 ASAI-II patients aged 2-7 years undergoing adenotonsillectomy and tonsillectomy were randomised into two groups. Analgesics were administered to the pre-emptive group before induction and to the intra-operative group 15 min after the start of surgery. In the recovery room, ED was assessed using the PAED scale and pain scores were assessed using the FLACC scores. PAED>10 was considered recovery delirium. The primary outcome was the incidence of recovery delirium. Secondary outcomes were delirium and pain scores. Results: PAED and FLACC scores were significantly lower in the preemptive group. There was a significant difference in the incidence of ED between the two groups only at 5 minutes. Conclusions: In children undergoing adenotonsillectomy and tonsillectomy, preemptive analgesia reduced postoperative pain scores and delirium scores, but did not reduce the incidence of recovery delirium.
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