脑瘫、诊断和现代治疗(文献综述)

S. K. Badu
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摘要

在大多数国家,每 500 名新生儿中就有 1 人患有脑瘫,全球发病率估计为 1 700 万,是儿童期最常见的终身肢体残疾原因。脑瘫 "一词是指一组儿童,他们的共同特征是在产前、围产期或产后早期遭受非进行性脑损伤或病变,而不是传统意义上的疾病实体。在脑瘫的临床症状中,运动异常的类型、功能能力和受限程度以及受影响的身体部位差异很大。虽然目前还没有治愈脑损伤的方法,但预防和治疗脑损伤的工作正在取得进展。虽然脑瘫会影响人的一生,但目前对这种疾病的研究工作和管理技术大多集中在儿童的需求上。已发现的治疗方法包括纳米医学、干细胞疗法、物理疗法、职业疗法以及药物和外科技术。要将脐带血疗法、纳米医学和干细胞疗法等疗法应用于临床,还需要进一步的研究。
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Cerebral palsy, diagnosis and modern treatment (literature review)
In most nations, cerebral palsy, which af fects 1 in 500 newborns and has an estimated incidence of 17 million people globally, is the most frequent cause of childhood-onset, lifelong physical disability. The term «cerebral palsy» refers to a group of children that share characteristics of a non-progressive brain injury or lesion that was sustained during antenatal, perinatal, or early postnatal life rather than a disease entity in the traditional sense. The type of movement abnormality, the degree of functional capacity and limitation, and the body areas affected vary widely among the clinical symptoms of cerebral palsy. Although there is presently no cure for brain injury, efforts to prevent and treat it are progressing. Although cerebral palsy affects people for their whole lives, the majority of research efforts and management techniques for the condition currently concentrate on the needs of children. The treatments discovered included nanomedicine, stem cell therapy, physiotherapy, occupational therapy, and medicinal and surgical techniques. Further research is required to adapt therapies like cord blood therapy, nanomedicine, and stem cell therapy in clinical settings.
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