{"title":"抗癌药物的 In - Silico 生物学评估 - SWISS ADME","authors":"Nizamuddin Nd, Roopa D, Pramodini Alla, Afshin Shams Shaik, Vamshi Kumar Achari P, Sudhakar Reddy Kapu","doi":"10.26452/fjphs.v4i2.604","DOIUrl":null,"url":null,"abstract":"The aim of the present work is to prepare anti-cancer drugs through In – Silico Biological Evaluation using SWISS ADME. The new Swiss ADME web tool, which includes in-house expert methods like the BOILED-Egg, Ilogp, and Bioavailability Radar, provides free access to a pool of quick yet reliable predictive models for physicochemical properties, pharmacokinetics, drug-likeness, and medicinal chemistry friendliness. It is developed to predict various pharmacodynamics and pharmacokinetics properties of small molecules, helping researchers in the drug discovery and development process. Researchers can use this tool to assess the potential success of a drug in terms of its ADME. Swiss ADME offers predictive model for various pharmacokinetic properties such as solubility, lipophilicity, and bioavailability this helps researchers assess how a drug candidate will be absorbed, distributed, metabolized, and excreted in the body.","PeriodicalId":503124,"journal":{"name":"Future Journal of Pharmaceuticals and Health Sciences","volume":" 5","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"In – Silico Biological Evaluation of Anticancer Drugs - SWISS ADME\",\"authors\":\"Nizamuddin Nd, Roopa D, Pramodini Alla, Afshin Shams Shaik, Vamshi Kumar Achari P, Sudhakar Reddy Kapu\",\"doi\":\"10.26452/fjphs.v4i2.604\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The aim of the present work is to prepare anti-cancer drugs through In – Silico Biological Evaluation using SWISS ADME. The new Swiss ADME web tool, which includes in-house expert methods like the BOILED-Egg, Ilogp, and Bioavailability Radar, provides free access to a pool of quick yet reliable predictive models for physicochemical properties, pharmacokinetics, drug-likeness, and medicinal chemistry friendliness. It is developed to predict various pharmacodynamics and pharmacokinetics properties of small molecules, helping researchers in the drug discovery and development process. Researchers can use this tool to assess the potential success of a drug in terms of its ADME. Swiss ADME offers predictive model for various pharmacokinetic properties such as solubility, lipophilicity, and bioavailability this helps researchers assess how a drug candidate will be absorbed, distributed, metabolized, and excreted in the body.\",\"PeriodicalId\":503124,\"journal\":{\"name\":\"Future Journal of Pharmaceuticals and Health Sciences\",\"volume\":\" 5\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future Journal of Pharmaceuticals and Health Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26452/fjphs.v4i2.604\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Journal of Pharmaceuticals and Health Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26452/fjphs.v4i2.604","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
In – Silico Biological Evaluation of Anticancer Drugs - SWISS ADME
The aim of the present work is to prepare anti-cancer drugs through In – Silico Biological Evaluation using SWISS ADME. The new Swiss ADME web tool, which includes in-house expert methods like the BOILED-Egg, Ilogp, and Bioavailability Radar, provides free access to a pool of quick yet reliable predictive models for physicochemical properties, pharmacokinetics, drug-likeness, and medicinal chemistry friendliness. It is developed to predict various pharmacodynamics and pharmacokinetics properties of small molecules, helping researchers in the drug discovery and development process. Researchers can use this tool to assess the potential success of a drug in terms of its ADME. Swiss ADME offers predictive model for various pharmacokinetic properties such as solubility, lipophilicity, and bioavailability this helps researchers assess how a drug candidate will be absorbed, distributed, metabolized, and excreted in the body.
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