早期检测:胰腺癌诊断中的机器学习技术

Mallipudi Devi Siva Sai, Palaparthi Prudhvi, Gollapudi M Naga Venkata Sai Gopi, Indla Ganeswara Naga Sai Ram, Mandadi Ram Sandeep, Nagababu Pachhala
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摘要

胰腺癌是一种对患者生命构成重大威胁的恶性肿瘤。恶性增生是细胞组织的异常发展。胰腺疾病是全球最明显的致死原因之一。胰腺恶性发展始于胰腺组织。胰腺分泌帮助消化的蛋白质以及指导糖分解的激素。胰腺癌通常在晚期才被发现,扩散迅速,预后很差。生物标记物对侵袭性恶性肿瘤患者的治疗至关重要。胰腺导管腺癌的预后很差,因为它已到了晚期,而且治疗方法有限。由于缺乏有效的筛查和预测生物标志物来进行早期检测和精准治疗,这种情况更加严重。在本文中,我们试图讨论检测胰腺癌的各种机器学习方法。所选的尿液生物标志物值被作为支持向量机(SVM)、额外树分类器(ETC)、决策树(DT)和随机森林(RF)方法的输入。使用 SVM、ETC、DT 和 RF 分类器诊断胰腺癌的准确率分别为 50、82.16、81.03 和 86。实验结果证明,与 ETC、DT 和 SVM 相比,随机森林分类器在胰腺癌诊断的临床应用中更可行、更有前景。
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Early Detection: Machine Learning Techniques in Pancreatic Cancer Diagnosis
Pancreatic cancer is a malignant tumor that poses a significant threat to patients' lives. Malignant growth is the abnormal development of cell tissue. Pancreatic illness is one of the most obvious causes of mortality across the world. Pancreatic malignant development begins in the pancreatic tissues. The pancreas secretes proteins that aid in digestion as well as hormones that direct sugar breakdown. Pancreatic cancer is typically identified in its late stages, spreads quickly, and has a terrible prognosis. Biomarkers are critical in the management of patients with invasive malignancies. Pancreatic Ductal Adenocarcinoma has a dismal prognosis due to its advanced appearance and limited treatment choices. This is compounded by the lack of validated screening and predicting biomarkers for early detection and precision therapy, respectively. In this paper, we have attempted to discuss various Machine Learning methods to detect pancreatic cancer. The selected. urinary biomarkers values are provided as the input of Support Vector Machine (SVM), Extra Tree Classifier (ETC), Decision Tree (DT), and Random Forest (RF) methods. The diagnosing accuracy of pancreatic cancer using SVM, ETC, DT, and RF classifiers are 50, 82.16, 81.03, and 86 respectively. The experimental results prove that the Random Forest classifier is more feasible and promising for clinical applications for the diagnosis of pancreatic cancer when compared to ETC, DT, and SVM.
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