构建循环重复测量设计类并有效控制结转效应的简单方法

IF 1.2 4区 综合性期刊 Q3 MULTIDISCIPLINARY SCIENCES Kuwait Journal of Science Pub Date : 2024-04-30 DOI:10.1016/j.kjs.2024.100237
Muhammad Riaz , Mahmood Ulhassan , H.M. Kashif Rasheed , Abid Khan , Rashid Ahmed
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引用次数: 0

摘要

重复测量设计(RMD)经济实惠,常用于药理学、心理学和动物科学实验。然而,重复测量设计可能会产生带入效应,这也是估计治疗效果时产生偏差的主要原因。使用最小平衡 RMD、强平衡 RMD 或其广义类别可以经济地控制带入效应。文献中没有获得这些重要 RMD 类别的通用程序。本文开发了一个 R 软件包,用于检查给定值 v 和 p 是否可能存在最小循环平衡 RMD 和强平衡 RMD(以及它们的广义类别),为可能的设计生成移位集,并计算所生成设计的分离效率和带入效应。
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A simple method to construct circular repeated measurement design classes and efficiently control carry over effects

Repeated measurement designs (RMDs) are economical and commonly utilized in pharmacology, psychology, and animal science experiments. However, RMDs might have carryover effects, which become the main source of bias in estimation of treatment effects. Carry over effects can economically be controlled with the use of minimal balanced RMDs, strongly balanced RMDs or their generalized classes. No general procedure is available in literature to obtain these important classes of RMDs. An R-Package has been developed in this article to check the given values v and p for the possible existence of minimal circular balanced and strongly balanced RMDs (along with their generalized classes), generate the sets of shifts for possible designs, and to calculate the efficiency of separability and carry over effects for the generated design.

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来源期刊
Kuwait Journal of Science
Kuwait Journal of Science MULTIDISCIPLINARY SCIENCES-
CiteScore
1.60
自引率
28.60%
发文量
132
期刊介绍: Kuwait Journal of Science (KJS) is indexed and abstracted by major publishing houses such as Chemical Abstract, Science Citation Index, Current contents, Mathematics Abstract, Micribiological Abstracts etc. KJS publishes peer-review articles in various fields of Science including Mathematics, Computer Science, Physics, Statistics, Biology, Chemistry and Earth & Environmental Sciences. In addition, it also aims to bring the results of scientific research carried out under a variety of intellectual traditions and organizations to the attention of specialized scholarly readership. As such, the publisher expects the submission of original manuscripts which contain analysis and solutions about important theoretical, empirical and normative issues.
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