Pub Date : 2024-09-12DOI: 10.1016/j.kjs.2024.100317
This investigation is intended to demonstrate the synergistic, antibacterial, and antioxidant activity produced by the combination of essential oils (EOs) from Moroccan Clinopodium nepeta (CNEO), Ruta montana (RMEO), and Dittrichia viscosa (DVEO) EOs. The phytochemistry profile, the antibacterial effect and the antioxidant ability of EOs were assessed separately. Then, an augmented-simplex-centroid design was used to optimize the antibacterial activity of EOs formulations against Escherichia coli (E. coli) and Micrococcus luteus (M. luteus). The mixture design was also used to maximize the radical scavenging activity and the ferric reducing antioxidant power. The results of this study revealed that the optimal combination against E. coli conformed to 25% RMEO, 50% CNEO, and 25% DVEO, while the optimal mixture estimated against M. luteus was adjusted by the binary combination of 36% RMEO and 64% CNEO. Furthermore, the optimal association expected for DPPH inhibition is 37% RMEO, 40% CNEO, and 23% DVEO, while the formulation of 30% RMEO, 38% CNEO, and 32% DVEO presented the maximal mixture to obtain the highest ferric reducing power. These data showed the effectiveness of EOs mixtures against resistant bacteria and their promising employment as natural antioxidant agents in foods.
{"title":"Mixture design as an innovative tool to optimize the antioxidant and antibacterial activity of moroccan essential oils: Clinopodium nepeta, Ruta montana, and Dittrichia viscosa","authors":"","doi":"10.1016/j.kjs.2024.100317","DOIUrl":"10.1016/j.kjs.2024.100317","url":null,"abstract":"<div><p>This investigation is intended to demonstrate the synergistic, antibacterial, and antioxidant activity produced by the combination of essential oils (EOs) from Moroccan <em>Clinopodium nepeta</em> (CNEO), <em>Ruta montana</em> (RMEO), and <em>Dittrichia viscosa</em> (DVEO) EOs. The phytochemistry profile, the antibacterial effect and the antioxidant ability of EOs were assessed separately. Then, an augmented-simplex-centroid design was used to optimize the antibacterial activity of EOs formulations against <em>Escherichia coli</em> (<em>E. coli</em>) and <em>Micrococcus luteus (M. luteus</em>). The mixture design was also used to maximize the radical scavenging activity and the ferric reducing antioxidant power. The results of this study revealed that the optimal combination against <em>E. coli</em> conformed to 25% RMEO, 50% CNEO, and 25% DVEO, while the optimal mixture estimated against <em>M. luteus</em> was adjusted by the binary combination of 36% RMEO and 64% CNEO. Furthermore, the optimal association expected for DPPH inhibition is 37% RMEO<em>,</em> 40% CNEO<em>,</em> and 23% DVEO, while the formulation of 30% RMEO<em>,</em> 38% CNEO<em>,</em> and 32% DVEO presented the maximal mixture to obtain the highest ferric reducing power. These data showed the effectiveness of EOs mixtures against resistant bacteria and their promising employment as natural antioxidant agents in foods.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2307410824001421/pdfft?md5=0a852999573fb93e52f43c0090722010&pid=1-s2.0-S2307410824001421-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142232676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-12DOI: 10.1016/j.kjs.2024.100313
Novel derivatives of potential angiotensin converting enzyme (ACE-I) inhibitors (compounds 5a-e) were synthesized by reacting homophthalic anhydride with methyl esters of L-amino acids (L-isoleucine, L-phenylalanine, L-tyrosine, L-methionine, and L-serine). This reaction resulted in yields of 85% for compound 5a, 83% for compound 5b, 84% for compound 5c, 80% for compound 5d, and 85% for compound 5e. All the synthesized compounds were characterized by 1D and 2D NMR methods. In silico ADME properties of compounds 5a-e conform to Lipinski's drug rules. The in silico toxicological determination of the synthesized compounds suggest that compound 5a exhibits significant potential for adverse effects, such as causing hormonal imbalances. In comparison, the remaining compounds 5b-c demonstrate a lower risk profile. In silico biological activities of compounds 5a-e in the active site of ACE-I were determined by docking, which were then compared to the FDA approved antihypertensive drugs enalalapril and lisinopril. Docking studies revealed that compound 5b (ΔGcomp = −8.851 kcal/mol) possesses the greatest binding affinity in the Zn2+ binding site of ACE-I compared to those of lisinoprilat (ΔGcomp = −8.066 kcal/mol) and enalapril (ΔGcomp = −7.187 kcal/mol), strongly suggesting a great potential to be a lead candidate for novel antihypertensive drug development.
{"title":"Design, synthesis, and structural investigations of novel (S)-amide derivatives as promising ACE inhibitors","authors":"","doi":"10.1016/j.kjs.2024.100313","DOIUrl":"10.1016/j.kjs.2024.100313","url":null,"abstract":"<div><p>Novel derivatives of potential angiotensin converting enzyme (ACE-I) inhibitors (compounds <strong>5a-e</strong>) were synthesized by reacting homophthalic anhydride with methyl esters of L-amino acids (L-isoleucine, L-phenylalanine, L-tyrosine, L-methionine, and L-serine). This reaction resulted in yields of 85% for compound <strong>5a</strong>, 83% for compound <strong>5b</strong>, 84% for compound <strong>5c</strong>, 80% for compound <strong>5d</strong>, and 85% for compound <strong>5e</strong>. All the synthesized compounds were characterized by 1D and 2D NMR methods. <em>In silico</em> ADME properties of compounds 5a-e conform to Lipinski's drug rules. The <em>in silico</em> toxicological determination of the synthesized compounds suggest that compound 5a exhibits significant potential for adverse effects, such as causing hormonal imbalances. In comparison, the remaining compounds 5b-c demonstrate a lower risk profile. <em>In silico</em> biological activities of compounds 5a-e in the active site of ACE-I were determined by docking, which were then compared to the FDA approved antihypertensive drugs enalalapril and lisinopril. Docking studies revealed that compound <strong>5b</strong> (ΔG<sup>comp</sup> = −8.851 kcal/mol) possesses the greatest binding affinity in the Zn<sup>2+</sup> binding site of ACE-I compared to those of lisinoprilat (ΔG<sup>comp</sup> = −8.066 kcal/mol) and enalapril (ΔG<sup>comp</sup> = −7.187 kcal/mol), strongly suggesting a great potential to be a lead candidate for novel antihypertensive drug development.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S230741082400138X/pdfft?md5=e492a879102cd71c0a83510b64ad4834&pid=1-s2.0-S230741082400138X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142173123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-12DOI: 10.1016/j.kjs.2024.100315
The present study employed microwave-assisted extraction (MAE) as a method to extract a crude extract high in polyphenols from the leaves of duku (Lansium domesticum Corr.), a medicinal plant indigenous to Indonesia. The study acquired data on the impact of various extraction parameters, such as ethanol concentration (X1), microwave power (X2), and extraction time (X3), on the levels of total phenolics content (TPC), total flavonoids content (TFC), and antioxidant activity using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) scavenging activity. The extraction process was optimized using a Box-Behnken design (BBD) and response surface methodology (RSM). The optimal conditions were achieved with an X1 of 75%, an X2 of 315 W, and an X3 of 8.5 min. The aforementioned experimental settings yielded results of 86.176 mg GAE/g, 31.585 mg QE/g, and 75.850% for the TPC, TFC, and antioxidant activity, respectively. The extract included several significant active chemicals, including octadecanoic acid, undecane, 2-methyl-, 9-octadecenoic acid (Z)-hexyl ester, pentadecanoic acid, 9-hexadecanoic acid, phenolic and flavonoid compounds. The cytotoxic activity against MCF-7, T47D, and 4T1 cell lines was found to be slowed when exposed to crude extract doses ranging from 7.81 to 500.00 μg/mL. The present study's results suggest that MAE is a viable technique for extracting a polyphenol-rich crude extract from duku leaf. This extract shows promise as a natural antioxidant and has potential as an anti-breast cancer agent.
{"title":"Optimization of microwave-assisted extraction to obtain a polyphenol-rich crude extract from duku (Lansium domesticum Corr.) leaf and the correlation with antioxidant and cytotoxic activities","authors":"","doi":"10.1016/j.kjs.2024.100315","DOIUrl":"10.1016/j.kjs.2024.100315","url":null,"abstract":"<div><p>The present study employed microwave-assisted extraction (MAE) as a method to extract a crude extract high in polyphenols from the leaves of duku (<em>Lansium domesticum</em> Corr.), a medicinal plant indigenous to Indonesia. The study acquired data on the impact of various extraction parameters, such as ethanol concentration (X<sub>1</sub>), microwave power (X<sub>2</sub>), and extraction time (X<sub>3</sub>), on the levels of total phenolics content (TPC), total flavonoids content (TFC), and antioxidant activity using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) scavenging activity. The extraction process was optimized using a Box-Behnken design (BBD) and response surface methodology (RSM). The optimal conditions were achieved with an X<sub>1</sub> of 75%, an X<sub>2</sub> of 315 W, and an X<sub>3</sub> of 8.5 min. The aforementioned experimental settings yielded results of 86.176 mg GAE/g, 31.585 mg QE/g, and 75.850% for the TPC, TFC, and antioxidant activity, respectively. The extract included several significant active chemicals, including octadecanoic acid, undecane, 2-methyl-, 9-octadecenoic acid (Z)-hexyl ester, pentadecanoic acid, 9-hexadecanoic acid, phenolic and flavonoid compounds. The cytotoxic activity against MCF-7, T47D, and 4T1 cell lines was found to be slowed when exposed to crude extract doses ranging from 7.81 to 500.00 μg/mL. The present study's results suggest that MAE is a viable technique for extracting a polyphenol-rich crude extract from duku leaf. This extract shows promise as a natural antioxidant and has potential as an anti-breast cancer agent.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2307410824001408/pdfft?md5=3b0b02cf757912163c3dcb1492a197b6&pid=1-s2.0-S2307410824001408-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142239395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-11DOI: 10.1016/j.kjs.2024.100316
In this study, the dyestuff and antimicrobial properties were examined using extracts obtained from mint (Mentha spicata L.) and thyme (Thymus vulgaris L.) plants. Cotton and woolen fabric samples were used in the dyeing process using pre–, meta–, post– mordant, and non–mordant dyeing methods. CuSO4, FeSO4, and AlK(SO4)2 mordants were used as stabilizers and color changers. The color analysis of the dyed textile samples was evaluated in terms of rubbing, washing, and light fastness values. The color codes were determined with the Pantone Color Guide, and the L∗, a∗, b∗, C∗, ho, and K/S values were detected with a color measurement spectrophotometer. The highest K/S value was measured as 23.050 for FeSO4 with meta–mordanting method for dyed wool yarn using thyme extract. The antimicrobial properties of the dyed fabrics were determined by the disk diffusion method. Among the mordants used, dyeing with CuSO4 showed better antimicrobial properties than other mordants. As the textile dyed products possess antimicrobial properties, we believe their use in health centers will make a positive contribution to hygiene. As a result, it was determined that extracts obtained from mint (Mentha spicata L.) and thyme (Thymus vulgaris L.) plants were effective natural dye sources for textile products.
{"title":"The use of mint and thyme extracts as eco–friendly natural dyes and the antimicrobial properties of dyed products","authors":"","doi":"10.1016/j.kjs.2024.100316","DOIUrl":"10.1016/j.kjs.2024.100316","url":null,"abstract":"<div><p>In this study, the dyestuff and antimicrobial properties were examined using extracts obtained from mint (<em>Mentha spicata</em> L.) and thyme (<em>Thymus vulgaris</em> L.) plants. Cotton and woolen fabric samples were used in the dyeing process using pre–, meta–, post– mordant, and non–mordant dyeing methods. CuSO<sub>4</sub>, FeSO<sub>4</sub>, and AlK(SO<sub>4</sub>)<sub>2</sub> mordants were used as stabilizers and color changers. The color analysis of the dyed textile samples was evaluated in terms of rubbing, washing, and light fastness values. The color codes were determined with the Pantone Color Guide, and the <em>L</em>∗, <em>a</em>∗, <em>b</em>∗, <em>C</em>∗, <em>h</em><sup>o</sup>, and <em>K/S</em> values were detected with a color measurement spectrophotometer. The highest <em>K/S</em> value was measured as 23.050 for FeSO<sub>4</sub> with meta–mordanting method for dyed wool yarn using thyme extract. The antimicrobial properties of the dyed fabrics were determined by the disk diffusion method. Among the mordants used, dyeing with CuSO<sub>4</sub> showed better antimicrobial properties than other mordants. As the textile dyed products possess antimicrobial properties, we believe their use in health centers will make a positive contribution to hygiene. As a result, it was determined that extracts obtained from mint (<em>Mentha spicata</em> L.) and thyme (<em>Thymus vulgaris</em> L.) plants were effective natural dye sources for textile products.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S230741082400141X/pdfft?md5=071cfbb0fb3bbaa803995516de83db58&pid=1-s2.0-S230741082400141X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142239394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-30DOI: 10.1016/j.kjs.2024.100311
Let be a simple undirected graph, and let be its Seidel matrix. The Seidel energy of is defined as , where are Seidel eigenvalues of . Recently, researchers have studied the effect of embedded edges on the distance energy of complete bipartite graphs. In this paper, the effect of perturbed edges on the Seidel energy of complete bipartite graphs and complete split graphs is studied. Finally, these graphs are ordered according to their Seidal energies.
设 G 是一个简单的无向图,S(G) 是它的塞德尔矩阵。G 的 Seidel 能量定义为 ES(G)=∑i=1n|λSi(G)| 其中,λS1(G),λS2(G),...,λSn(G) 是 G 的 Seidel 特征值。最近,研究人员研究了嵌入边对完整双向图距离能量的影响。本文研究了扰动边对完整双方图和完整分裂图的 Seidel 能量的影响。最后,根据这些图的塞德尔能对它们进行了排序。
{"title":"Effects on Seidel energy of two special types of graphs by perturbing edges","authors":"","doi":"10.1016/j.kjs.2024.100311","DOIUrl":"10.1016/j.kjs.2024.100311","url":null,"abstract":"<div><p>Let <span><math><mi>G</mi></math></span> be a simple undirected graph, and let <span><math><mrow><mi>S</mi><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow></mrow></math></span> be its Seidel matrix. The Seidel energy of <span><math><mi>G</mi></math></span> is defined as <span><math><mrow><msub><mrow><mi>E</mi></mrow><mrow><mi>S</mi></mrow></msub><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow><mo>=</mo><msubsup><mrow><mo>∑</mo></mrow><mrow><mi>i</mi><mo>=</mo><mn>1</mn></mrow><mrow><mi>n</mi></mrow></msubsup><mrow><mo>|</mo><msub><mrow><mi>λ</mi></mrow><mrow><msub><mrow><mi>S</mi></mrow><mrow><mi>i</mi></mrow></msub></mrow></msub><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow><mo>|</mo></mrow></mrow></math></span>, where <span><math><mrow><msub><mrow><mi>λ</mi></mrow><mrow><msub><mrow><mi>S</mi></mrow><mrow><mn>1</mn></mrow></msub></mrow></msub><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow><mo>,</mo><msub><mrow><mi>λ</mi></mrow><mrow><msub><mrow><mi>S</mi></mrow><mrow><mn>2</mn></mrow></msub></mrow></msub><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow><mo>,</mo><mo>…</mo><mo>,</mo><msub><mrow><mi>λ</mi></mrow><mrow><msub><mrow><mi>S</mi></mrow><mrow><mi>n</mi></mrow></msub></mrow></msub><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow></mrow></math></span> are Seidel eigenvalues of <span><math><mi>G</mi></math></span>. Recently, researchers have studied the effect of embedded edges on the distance energy of complete bipartite graphs. In this paper, the effect of perturbed edges on the Seidel energy of complete bipartite graphs and complete split graphs is studied. Finally, these graphs are ordered according to their Seidal energies.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2307410824001366/pdfft?md5=21ca43aba48460704d798ad7853a4947&pid=1-s2.0-S2307410824001366-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142122764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-28DOI: 10.1016/j.kjs.2024.100310
Migraines are classified as a neurological disorder defined by recurrent headaches with pain that ranges from mild to severe. Currently, this disorder lacks a permanent cure and definitive diagnostic test. Diagnosis instead requires an assessment of physical and psychological symptoms which differ among patients. To help in the diagnosis process, medical expert systems have been developed and validated since 1960. In this paper, we propose the Migraine Diagnosis and Treatment Expert System (MDATES), a medical expert system for migraine diagnosis and treatment recommendation. The system was designed and implemented using the C Language Integrated Production System (CLIPS) shell. MDATES is able to recognize seven symptoms, two classes of migraines (chronic and episodic), and four subtypes of migraine-classification knowledge (hormonal, aura, hemiplegic, and cluster). A dataset of 300 anonymized patient records with confirmed migraine cases was used to test the system. The diagnoses generated by MDATES were compared against the known diagnoses, and a high level of accuracy was observed, with 67% of the 100 training cases were correctly diagnosed, and 100% of the 200 testing cases were correctly diagnosed. These results highlight the effectiveness and reliability of MDATES and provide valuable assistance to medical professionals in diagnosing migraines. Moreover, we present a literature review that places our proposed system within the broader context of rule-based expert systems for migraine diagnosis and treatment recommendation. This review explores the effectiveness, limitations, and challenges of these systems, and accurately places our system within the current landscape.
{"title":"A novel CLIPS-based medical expert system for migraine diagnosis and treatment recommendation","authors":"","doi":"10.1016/j.kjs.2024.100310","DOIUrl":"10.1016/j.kjs.2024.100310","url":null,"abstract":"<div><p>Migraines are classified as a neurological disorder defined by recurrent headaches with pain that ranges from mild to severe. Currently, this disorder lacks a permanent cure and definitive diagnostic test. Diagnosis instead requires an assessment of physical and psychological symptoms which differ among patients. To help in the diagnosis process, medical expert systems have been developed and validated since 1960. In this paper, we propose the Migraine Diagnosis and Treatment Expert System (MDATES), a medical expert system for migraine diagnosis and treatment recommendation. The system was designed and implemented using the C Language Integrated Production System (CLIPS) shell. MDATES is able to recognize seven symptoms, two classes of migraines (chronic and episodic), and four subtypes of migraine-classification knowledge (hormonal, aura, hemiplegic, and cluster). A dataset of 300 anonymized patient records with confirmed migraine cases was used to test the system. The diagnoses generated by MDATES were compared against the known diagnoses, and a high level of accuracy was observed, with 67% of the 100 training cases were correctly diagnosed, and 100% of the 200 testing cases were correctly diagnosed. These results highlight the effectiveness and reliability of MDATES and provide valuable assistance to medical professionals in diagnosing migraines. Moreover, we present a literature review that places our proposed system within the broader context of rule-based expert systems for migraine diagnosis and treatment recommendation. This review explores the effectiveness, limitations, and challenges of these systems, and accurately places our system within the current landscape.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2307410824001354/pdfft?md5=029bcc9c4716f74ac323c90ecbbe5cf8&pid=1-s2.0-S2307410824001354-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142122607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-02DOI: 10.1016/j.kjs.2024.100309
Oil palm (Elaeis guineensis Jacq.) is the primary source of foreign exchange in Indonesia's plantation sector. However, these plants are very vulnerable to attack by Ganoderma spp., which causes basal stem rot (BSR) and upper stem rot (USR) disease, resulting in significant economic losses. In this study, antagonistic assays of the G17 isolate obtained from the gut of black soldier fly (BSF) larvae showed potential biocontrol against G. boninense. Furthermore, antibiosis assays showed that the Stenotrophomonas maltophilia G17 isolate inhibited the growth of G. boninense by up to 85.56%–91.98%. Molecular identification using 16S rRNA, reinforced by biochemical characterization tests, confirmed the G17 isolate as S. maltophilia. Growth test results showed that S. maltophilia G17 cannot grow at a temperature of 37 °C within 24 h. The isolate also exhibited negative hemolytic activity, indicating it is not a pathogenic bacterium. S. maltophilia G17 exhibited lytic enzymes such as proteolytic, lipolytic, and chitinolytic activity. Among them, chitinolytic enzymes might be involved in the biocontrol process.
{"title":"Stenotrophomonas maltophilia G17: Potential antifungal agent isolated from the gut of black soldier fly larvae against Ganoderma boninense","authors":"","doi":"10.1016/j.kjs.2024.100309","DOIUrl":"10.1016/j.kjs.2024.100309","url":null,"abstract":"<div><p>Oil palm (<em>Elaeis guineensis</em> Jacq.) is the primary source of foreign exchange in Indonesia's plantation sector. However, these plants are very vulnerable to attack by <em>Ganoderma</em> spp., which causes basal stem rot (BSR) and upper stem rot (USR) disease, resulting in significant economic losses. In this study, antagonistic assays of the G17 isolate obtained from the gut of black soldier fly (BSF) larvae showed potential biocontrol against <em>G. boninense</em>. Furthermore, antibiosis assays showed that the <em>Stenotrophomonas maltophilia</em> G17 isolate inhibited the growth of <em>G. boninense</em> by up to 85.56%–91.98%. Molecular identification using 16S rRNA, reinforced by biochemical characterization tests, confirmed the G17 isolate as <em>S</em>. <em>maltophilia.</em> Growth test results showed that <em>S. maltophilia</em> G17 cannot grow at a temperature of 37 °C within 24 h. The isolate also exhibited negative hemolytic activity, indicating it is not a pathogenic bacterium. <em>S. maltophilia</em> G17 exhibited lytic enzymes such as proteolytic, lipolytic, and chitinolytic activity. Among them, chitinolytic enzymes might be involved in the biocontrol process.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2307410824001342/pdfft?md5=218c951a3ff103cd4e05e9ad65175137&pid=1-s2.0-S2307410824001342-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141963030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-26DOI: 10.1016/j.kjs.2024.100308
Failaka Island has a marina, which was constructed in 1979 and managed by the Ministry of Communication (MOC) in collaboration with Touristic Enterprises Company (TEC). The marina is widely used for its ferry landing facility. The coastal waters around Failaka are turbid, and current velocities tend to be as high as ∼0.5 m/s during spring tide. The marina basin, with axial plane view and dimensions of about 285m by 260m, experiences shoaling of naturally flocculated fine (cohesive) sediment and coarse sand at the entrance of the channel and more generally in the southern half of the basin. Particularly noteworthy is its heavy shoaling zone along the inner side of the south breakwater close to the entrance. The Failaka island marina is suffering from siltation and sediment deposition issues. The study was carried out numerically to assess the annual sedimentation, sediment direction, and longshore current from different locations around the marina and recommend solutions to reduce the siltation and sediment deposition based on sediment transport direction at the marina entrance. The study shows that the sediment is mostly transported to the Failaka marina entrance from the southeast due to wave action. The cumulative sediment transport for the period 2016 to 2020 as depicted from locations 1 and 2, which are vulnerable to the southeast waves, is 9,164 m3 and 12,323 m3. The annual sediment transport direction affecting the marina is oriented from south to north due to wave action.
{"title":"Modeling of sediment transport direction affecting Failaka island marina bathymetry, Kuwait","authors":"","doi":"10.1016/j.kjs.2024.100308","DOIUrl":"10.1016/j.kjs.2024.100308","url":null,"abstract":"<div><p>Failaka Island has a marina, which was constructed in 1979 and managed by the Ministry of Communication (MOC) in collaboration with Touristic Enterprises Company (TEC). The marina is widely used for its ferry landing facility. The coastal waters around Failaka are turbid, and current velocities tend to be as high as ∼0.5 m/s during spring tide. The marina basin, with axial plane view and dimensions of about 285m by 260m, experiences shoaling of naturally flocculated fine (cohesive) sediment and coarse sand at the entrance of the channel and more generally in the southern half of the basin. Particularly noteworthy is its heavy shoaling zone along the inner side of the south breakwater close to the entrance. The Failaka island marina is suffering from siltation and sediment deposition issues. The study was carried out numerically to assess the annual sedimentation, sediment direction, and longshore current from different locations around the marina and recommend solutions to reduce the siltation and sediment deposition based on sediment transport direction at the marina entrance. The study shows that the sediment is mostly transported to the Failaka marina entrance from the southeast due to wave action. The cumulative sediment transport for the period 2016 to 2020 as depicted from locations 1 and 2, which are vulnerable to the southeast waves, is 9,164 m<sup>3</sup> and 12,323 m<sup>3</sup>. The annual sediment transport direction affecting the marina is oriented from south to north due to wave action.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2307410824001330/pdfft?md5=96611bc8ba2d46ca5d32e7f491dd2d52&pid=1-s2.0-S2307410824001330-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141848305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-25DOI: 10.1016/j.kjs.2024.100296
The aim of this study is to examine the relationships between height growth and some site factors of Crimean juniper in southwestern Anatolia. The data was collected from 130 sample plots selected from 10 districts in western Anatolia. The age and height of the Crimean juniper were measured in each sample plot. Surface soil samples collected from each sample plot were analyzed for pH, organic matter, carbonate content, texture, stoniness, available water capacity, wilting point, and field capacity. All site index values were calculated at a standard age of 100 years old. Spearman and Pearson correlation analyses were used to determine the relationships between plus tree and site factors. According to Spearman's correlation analysis, the site index showed a negative relationship with limestone. According to the results of the Pearson correlation analysis, the numerical variables LATTUD, SLOPE, SURSTON, and HINDEX had a 1% relationship with the site index, and RINDEX had a 5% relationship. Once the binary relationships had been determined, the multivariate relationships were modelled using generalized additive models. The best site index model was obtained using a generalized additive model 1 (R = 0.63), including latitude, longitude, altitude, slope, and stoniness.
{"title":"Relationships between site index modeling of crimean juniper and habitat factors","authors":"","doi":"10.1016/j.kjs.2024.100296","DOIUrl":"10.1016/j.kjs.2024.100296","url":null,"abstract":"<div><p>The aim of this study is to examine the relationships between height growth and some site factors of Crimean juniper in southwestern Anatolia. The data was collected from 130 sample plots selected from 10 districts in western Anatolia. The age and height of the Crimean juniper were measured in each sample plot. Surface soil samples collected from each sample plot were analyzed for pH, organic matter, carbonate content, texture, stoniness, available water capacity, wilting point, and field capacity. All site index values were calculated at a standard age of 100 years old. Spearman and Pearson correlation analyses were used to determine the relationships between plus tree and site factors. According to Spearman's correlation analysis, the site index showed a negative relationship with limestone. According to the results of the Pearson correlation analysis, the numerical variables LATTUD, SLOPE, SURSTON, and HINDEX had a 1% relationship with the site index, and RINDEX had a 5% relationship. Once the binary relationships had been determined, the multivariate relationships were modelled using generalized additive models. The best site index model was obtained using a generalized additive model 1 (R = 0.63), including latitude, longitude, altitude, slope, and stoniness.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2307410824001214/pdfft?md5=b9c8d02d92cfd7b7220087398c29c8d8&pid=1-s2.0-S2307410824001214-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141953050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-25DOI: 10.1016/j.kjs.2024.100307
Aeromagnetic data over parts of the Northern Anambra and Southern Bida basins have been evaluated with emphasis on the subsurface geologic structures controlling mineralization and delineating the geomorphology of the basin. Four aeromagnetic data sheets (246 (Kabba), 247 (Lokoja), 266 (Auchi), and 267 (Idah)) were acquired through purchase, assemblage, analysis, and interpretation using integrated processing techniques of Euler deconvolution, analytical signal (AS), source parameter imaging (SPI), and 3D magnetic inversion model. The data are collected laterally in a series of NW-SE trajectories spaced 2 km apart, with an average flight altitude of approximately 150 m, and tielines occurring at approximately 20 km intervals. Qualitative observation of TMI and RAM shows that the research region is greatly fractured, with structures orienting in the E-W direction. The spectral analysis result shows that the sedimentary infillings range from 0.60 to 4.03 km. 3D model and curie isotherm depth subsurface maps reveal deeper curie depths at Kabba, Adavi, and Itakpe zones (28.0–40.0 km) and shallow curie depths at Auchi, Osara, Idah, and Anyigba areas (18.0–27.0 km). The result from the heat flow model shows an inverse relationship with the Curie isotherm depth. The contact depth sources calculated from Euler depth assessments show that the majority of these contact sources are trending in the E-W directions. The overall structural geomorphology of the research region conforms to the general pattern of structural trends within the research region. Most of the structures are trending NNE-SSW, NNW-SSE, and NE-SW, while the minor structures trend in the E-W direction. 3D inversion results show a discrete subsurface geologic structure that may house minerals within the region.
{"title":"Structural modelling of subsurface geologic structures in Anambra and adjoining Bida Basins using aeromagnetic data: Implications for mineral explorations.","authors":"","doi":"10.1016/j.kjs.2024.100307","DOIUrl":"10.1016/j.kjs.2024.100307","url":null,"abstract":"<div><p>Aeromagnetic data over parts of the Northern Anambra and Southern Bida basins have been evaluated with emphasis on the subsurface geologic structures controlling mineralization and delineating the geomorphology of the basin. Four aeromagnetic data sheets (246 (Kabba), 247 (Lokoja), 266 (Auchi), and 267 (Idah)) were acquired through purchase, assemblage, analysis, and interpretation using integrated processing techniques of Euler deconvolution, analytical signal (AS), source parameter imaging (SPI), and 3D magnetic inversion model. The data are collected laterally in a series of NW-SE trajectories spaced 2 km apart, with an average flight altitude of approximately 150 m, and tielines occurring at approximately 20 km intervals. Qualitative observation of TMI and RAM shows that the research region is greatly fractured, with structures orienting in the E-W direction. The spectral analysis result shows that the sedimentary infillings range from 0.60 to 4.03 km. 3D model and curie isotherm depth subsurface maps reveal deeper curie depths at Kabba, Adavi, and Itakpe zones (28.0–40.0 km) and shallow curie depths at Auchi, Osara, Idah, and Anyigba areas (18.0–27.0 km). The result from the heat flow model shows an inverse relationship with the Curie isotherm depth. The contact depth sources calculated from Euler depth assessments show that the majority of these contact sources are trending in the E-W directions. The overall structural geomorphology of the research region conforms to the general pattern of structural trends within the research region. Most of the structures are trending NNE-SSW, NNW-SSE, and NE-SW, while the minor structures trend in the E-W direction. 3D inversion results show a discrete subsurface geologic structure that may house minerals within the region.</p></div>","PeriodicalId":17848,"journal":{"name":"Kuwait Journal of Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2307410824001329/pdfft?md5=69fdedcc4a9b052cdc48298ed244c8f9&pid=1-s2.0-S2307410824001329-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141842512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}