口腔鳞状细胞癌的颈部手术治疗。

Q4 Biochemistry, Genetics and Molecular Biology Critical Reviews in Oncogenesis Pub Date : 2024-01-01 DOI:10.1615/CritRevOncog.2023050817
Olivia Mihulka, Eric Nisenbaum, Elizabeth Nicolli
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引用次数: 0

摘要

口腔癌仍然是全球发病率和死亡率的重要原因,一旦转移到颈部淋巴结,预后很差。颈部淋巴引流的解剖结构为我们评估转移提供了路线图,尽管预测因素仍不十分清楚。治疗的主要方法仍然是颈部清扫术。然而,对于临床阴性颈部淋巴结的处理仍存在很多争议。近年来,随着前哨淋巴结活检等其他方法的流行,选择性颈部切除术的必要性受到质疑。本综述将探讨口腔癌颈部手术治疗的各个方面,并强调需要进一步开展的研究。
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Surgical Management of the Neck in Oral Cavity Squamous Cell Carcinoma.

Oral cavity cancer remains a significant cause of morbidity and mortality globally, with a poor prognosis once the disease has metastasized to cervical lymph nodes. The anatomy of lymphatic drainage in the neck gives us a roadmap to follow when assessing for metastasis, although the predictive factors are still not well understood. The mainstay of treatment continues to be neck dissection. However, there is much debate on the management of the clinically negative neck. The necessity of elective neck dissection has been questioned in recent years, with other options such as sentinel lymph node biopsy gaining popularity. This review will explore the aspects of surgical management of the neck in oral cavity cancer and highlights the further research that needs to be done.

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来源期刊
Critical Reviews in Oncogenesis
Critical Reviews in Oncogenesis Biochemistry, Genetics and Molecular Biology-Cancer Research
CiteScore
1.70
自引率
0.00%
发文量
17
期刊介绍: The journal is dedicated to extensive reviews, minireviews, and special theme issues on topics of current interest in basic and patient-oriented cancer research. The study of systems biology of cancer with its potential for molecular level diagnostics and treatment implies competence across the sciences and an increasing necessity for cancer researchers to understand both the technology and medicine. The journal allows readers to adapt a better understanding of various fields of molecular oncology. We welcome articles on basic biological mechanisms relevant to cancer such as DNA repair, cell cycle, apoptosis, angiogenesis, tumor immunology, etc.
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