混合深度学习辅助多重分类:恶性甲状腺结节分级

IF 2.2 4区 医学 Q3 ENGINEERING, BIOMEDICAL International Journal for Numerical Methods in Biomedical Engineering Pub Date : 2024-05-12 DOI:10.1002/cnm.3824
Mayuresh Bhagavat Gulame, Vaibhav V. Dixit
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引用次数: 0

摘要

甲状腺结节通常通过超声波诊断,其内部特征、外观各异、边界模糊,这使得临床医生仅凭视觉识别来区分恶性和良性结节极具挑战性。人工智能尤其是 DL 的发展为医学图像识别领域带来了重大突破。然而,要实现甲状腺结节检测的准确性和有效性还存在一定的障碍。本研究采用一种创造性的混合深度学习辅助多分类方法对甲状腺结节进行检测和分类。本研究采用中值模糊法消除图像中的椒盐噪声。然后利用基于 MPIU-Net 的分割法对图像进行分割。从分割后的图像中提取基于 LGBPNP 的特征,以获得 LGBP 模式的单一直方图序列,以及其他特征,如提取基于多文本和 LTP 的特征。提取特征后,应用数据增强过程,然后将特征输入由 Deep Maxout 和 CNN 组成的基于混合分类的结节分类模型,该混合分类模型训练特征并预测甲状腺结节。此外,TIRADS 评分分类与从分割中收集的统计特征相结合,用于预测恶性甲状腺结节。采用带有迁移学习模型的 DBNAAF 对恶性甲状腺结节进行分级,模型的权重是通过迁移学习获得的。混合模型的 MCC 为 0.9445,而 DCNN 为 0.6858,YOLOV3-DMRF 为 0.7229,CNN 为 0.7780,DBN 为 0.7601,Bi-GRU 为 0.7038,Deep Maxout 为 0.7528,RNN 为 0.8522。
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Hybrid deep learning assisted multi classification: Grading of malignant thyroid nodules

Thyroid nodules are commonly diagnosed with ultrasonography, which includes internal characteristics, varying looks, and hazy boundaries, making it challenging for a clinician to differentiate between malignant and benign forms based only on visual identification. The advancement of AI, particularly DL, provides significant breakthroughs in the domain of medical image identification. Yet, there are certain obstacles to achieving accuracy as well as efficacy in thyroid nodule detection. The thyroid nodules in this study are detected and classified using an inventive hybrid deep learning-assisted multi-classification method. The median blur method is applied in this work to eliminate the salt and pepper noise from the image. Then MPIU-Net-based segmentation is utilized to segment the image. The LGBPNP-based features are retrieved from the segmented image to obtain a single histogram sequence of the LGBP pattern in addition to other features like extraction of multi-texton and LTP-based features. After the feature extraction, the data augmentation process is applied and then the features are fed to the hybrid classification-based nodule classification model that comprises Deep Maxout and CNN, this hybrid classification trains the features and predicts the thyroid nodule. Additionally, the TIRADS score classification is used for the projected malignant thyroid nodule coupled with statistical features collected from the segmented. The DBNAAF with transfer learning model is employed to classify the grading of malignant thyroid nodules, where the weights of the model are learned with transfer learning. The MCC of the Hybrid Model is 0.9445, whereas the DCNN is 0.6858, YOLOV3-DMRF is 0.7229, CNN is 0.7780, DBN is 0.7601, Bi-GRU is 0.7038, Deep Maxout is 0.7528, and RNN is 0.8522, respectively.

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来源期刊
International Journal for Numerical Methods in Biomedical Engineering
International Journal for Numerical Methods in Biomedical Engineering ENGINEERING, BIOMEDICAL-MATHEMATICAL & COMPUTATIONAL BIOLOGY
CiteScore
4.50
自引率
9.50%
发文量
103
审稿时长
3 months
期刊介绍: All differential equation based models for biomedical applications and their novel solutions (using either established numerical methods such as finite difference, finite element and finite volume methods or new numerical methods) are within the scope of this journal. Manuscripts with experimental and analytical themes are also welcome if a component of the paper deals with numerical methods. Special cases that may not involve differential equations such as image processing, meshing and artificial intelligence are within the scope. Any research that is broadly linked to the wellbeing of the human body, either directly or indirectly, is also within the scope of this journal.
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