Tejasree Thutkur, Raja Shekhar Nunavath, Krishnaveni Nagappan
{"title":"揭开杂质分析的神秘面纱:全面探索确保中草药制剂质量和安全的新型分析技术","authors":"Tejasree Thutkur, Raja Shekhar Nunavath, Krishnaveni Nagappan","doi":"10.1016/j.ejmcr.2024.100166","DOIUrl":null,"url":null,"abstract":"<div><p>Herbal Phytoconstituents, also known as traditional medicines are considered to be harmless with no side effects. Herbal medicines have a global market value of 60 billion and have become increasingly popular in Western communities. Recent studies indicate that many herbal formulations in the market today have not been tested for quality and efficacy. The research outcomes suggest that, a proper quality check is necessary with novel analytical techniques to ensure product's safety. Thus, the impurities and their limits in herbal formulations should be examined as per pharmacopeial standards guidelines. The present review article emphasizes the importance of impurity profiling in herbal formulations and its significant role in natural product quality control. This article also suggests utilizing simple, precise and accurate, analytical methods to eliminate impurities, adulteration and combined synthetic chemicals in herbal products. In conclusion, implementing stricter regulations and creating public awareness about natural product safety measures can eradicate these adulterations since herbal formulations are in high demand in the commercial market after COVID-19.</p></div>","PeriodicalId":12015,"journal":{"name":"European Journal of Medicinal Chemistry Reports","volume":"11 ","pages":"Article 100166"},"PeriodicalIF":0.0000,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772417424000384/pdfft?md5=6b31aaa88f15ffc1c64a45c11f9f435c&pid=1-s2.0-S2772417424000384-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Unveiling the significance of impurity profiling: A comprehensive exploration of novel analytical techniques for ensuring quality and safety in herbal formulations\",\"authors\":\"Tejasree Thutkur, Raja Shekhar Nunavath, Krishnaveni Nagappan\",\"doi\":\"10.1016/j.ejmcr.2024.100166\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Herbal Phytoconstituents, also known as traditional medicines are considered to be harmless with no side effects. Herbal medicines have a global market value of 60 billion and have become increasingly popular in Western communities. Recent studies indicate that many herbal formulations in the market today have not been tested for quality and efficacy. The research outcomes suggest that, a proper quality check is necessary with novel analytical techniques to ensure product's safety. Thus, the impurities and their limits in herbal formulations should be examined as per pharmacopeial standards guidelines. The present review article emphasizes the importance of impurity profiling in herbal formulations and its significant role in natural product quality control. This article also suggests utilizing simple, precise and accurate, analytical methods to eliminate impurities, adulteration and combined synthetic chemicals in herbal products. In conclusion, implementing stricter regulations and creating public awareness about natural product safety measures can eradicate these adulterations since herbal formulations are in high demand in the commercial market after COVID-19.</p></div>\",\"PeriodicalId\":12015,\"journal\":{\"name\":\"European Journal of Medicinal Chemistry Reports\",\"volume\":\"11 \",\"pages\":\"Article 100166\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772417424000384/pdfft?md5=6b31aaa88f15ffc1c64a45c11f9f435c&pid=1-s2.0-S2772417424000384-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Medicinal Chemistry Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772417424000384\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Medicinal Chemistry Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772417424000384","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Unveiling the significance of impurity profiling: A comprehensive exploration of novel analytical techniques for ensuring quality and safety in herbal formulations
Herbal Phytoconstituents, also known as traditional medicines are considered to be harmless with no side effects. Herbal medicines have a global market value of 60 billion and have become increasingly popular in Western communities. Recent studies indicate that many herbal formulations in the market today have not been tested for quality and efficacy. The research outcomes suggest that, a proper quality check is necessary with novel analytical techniques to ensure product's safety. Thus, the impurities and their limits in herbal formulations should be examined as per pharmacopeial standards guidelines. The present review article emphasizes the importance of impurity profiling in herbal formulations and its significant role in natural product quality control. This article also suggests utilizing simple, precise and accurate, analytical methods to eliminate impurities, adulteration and combined synthetic chemicals in herbal products. In conclusion, implementing stricter regulations and creating public awareness about natural product safety measures can eradicate these adulterations since herbal formulations are in high demand in the commercial market after COVID-19.