关于富血小板血浆治疗慢性足底筋膜炎效果的前瞻性研究

A. M. I. Basha, Shaik Rasool, K. Anusha
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引用次数: 0

摘要

目标:本研究的目标如下(1)评估单剂量富血小板血浆(PRP)注射对足跟痛视觉模拟量表(VAS)评分的影响。(2)评估 PRP 治疗慢性足底筋膜炎后的功能结果评分。(3) 通过超声波(USG)评估,测量并确认足底筋膜厚度的恢复情况。(4)确定局部注射 PRP 作为慢性足底筋膜炎患者治疗方案的安全性和可行性:这项基于医院的前瞻性病例系列研究于 2019 年 1 月至 2020 年 1 月进行,共招募了 40 名年龄在 25-65 岁之间、患有单侧顽固性足底筋膜炎且保守治疗无效的患者。排除标准包括体重指数≥30、各种病症和近期注射过针剂。在获得伦理许可后,参与者接受了自体 PRP 注射,并通过超声波测量足底筋膜厚度。注射后,患者接受不良反应监测,开始伸展运动,6周后进行负重活动:研究对象平均年龄为 45 岁(标准差 [SD] 7.7),以女性为主,右脚居多。症状持续时间平均为 20 周(标准差为 4.5)。注射前的 VAS 评分(6.7±1.2)在 PRP 注射后 6 周(2.9±0.6)和 12 周(2.0±0.9)时明显改善(p<0.001)。12 周时,足底筋膜厚度从 5.1 毫米(标清 0.6)减至 4.1 毫米(标清 0.5)(p<0.001),常规足厚度从 3.7 毫米(标清 0.5)减至 4.1 毫米(标清 0.5)(p<0.001):结论:研究显示,单一的 PRP 注射可显著改善足跟疼痛、功能性结果和足底筋膜厚度的恢复,超声波测量结果也证明了这一点。这凸显了局部注射 PRP 是慢性足底筋膜炎患者可行且安全的治疗选择。
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PROSPECTIVE STUDY ON THE EFFECTIVENESS OF PLATELET-RICH PLASMA IN MANAGING CHRONIC PLANTAR FASCIITIS
Objectives: The objectives of this study were as follows: (1) Assess the impact of a single dose of platelet-rich plasma (PRP) injection on visual analog scale (VAS) scores for heel pain. (2) Evaluate the functional outcome scores following PRP treatment for chronic plantar fasciitis. (3) Measure and confirm the restoration of plantar fascia thickness through ultrasound (USG) assessments. (4) Determine the safety and viability of local PRP injection as a treatment option for individuals with chronic plantar fasciitis. Methods: This hospital-based prospective case series, spanning January 2019 to January 2020, enrolled 40 participants aged 25–65 with unilateral, persistent plantar fasciitis resistant to conservative treatment. Exclusion criteria included BMI ≥30, various pathologies, and recent injections. Ethical clearance was obtained, and participants received autologous PRP injections, with ultrasound measuring plantar fascia thickness. Post-injection, patients were monitored for adverse reactions, initiated stretching exercises, and progressed to weight-bearing activities after 6 weeks. Results: The study cohort, averaging 45 years (standard deviation [SD] 7.7), primarily comprised females with the right-foot prevalence. Symptom duration averaged 20 weeks (SD 4.5). Pre-injection VAS scores (6.7±1.2) significantly improved at 6 weeks (2.9±0.6) and 12 weeks (2.0±0.9) post-PRP injection (p<0.001). Plantar fascia thickness reduced from 5.1 mm (SD 0.6) to 4.1 mm (SD 0.5) at 12 weeks (p<0.001) and regular foot thickness: 3.7 mm (SD 0.5). Conclusion: The study reveals that a singular PRP injection brings about substantial and clinically meaningful enhancements in heel pain, functional outcomes, and the restoration of plantar fascia thickness, supported by ultrasound measurements. This underscores local PRP injection as a viable and safe therapeutic choice for those grappling with chronic plantar fasciitis.
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