食用可可对未经治疗的老年高血压患者餐后血压的影响:随机交叉临床试验

IF 7.4 Q1 FOOD SCIENCE & TECHNOLOGY Food frontiers Pub Date : 2024-05-06 DOI:10.1002/fft2.414
Emmanuel Ofori Osei, Isaac Amoah, Jia Jiet Lim, Phyllis Tawiah, Margaret Saka Aduama-Larbi, Ibok Nsa Oduro, Jesse Charles Cobbinah, Andrew Patrick Dare, Charles Diako
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引用次数: 0

摘要

可可粉是黄烷醇的重要膳食来源,可调节血压(BP)升高。本研究旨在调查可可饮料与高脂高盐膳食(HFHSM)同时食用对未控制高血压的老年人餐后收缩压(SBP)、舒张压(DBP)和心率的急性影响。该研究是一项随机交叉试验,涉及患有高血压的老年人(年龄为 52.50 ± 9.36 岁)(n = 28)。参与者在一夜禁食后,饮用由 250 毫升水兑 15 克可可粉组成的 HFHSM 和可可饮料(HFHSM + CB;干预)或 HFHSM 和 250 毫升水(HFHSM + W;对照)。在基线(-5 分钟和 0 分钟)和食用 HFHSM + CB 或 HFHSM + W 后的 15、30、45、60、90 和 120 分钟,使用自动血压监测仪测量参与者的静态 SBP、DBP 和心率。采用重复测量线性混合模型比较了可可饮料和水在 2 小时内对餐后结果的影响。与 HFHSM + W 相比,120 分钟内摄入 HFHSM + CB 后餐后静息 SBP 明显降低(-3.8 ± 0.6 mmHg,p < .05)。与 HFHSM + W 相比,饮用 HFHSM + CB 后的 DBP 和心率没有明显变化。可可饮料与 HFHSM 同饮可改善患有高血压的老年人的餐后 SBP。
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Effect of cocoa consumption on postprandial blood pressure in older adults with untreated hypertension: A randomized crossover clinical trial

Cocoa powder is an important dietary source of flavanols that modulate elevated blood pressure (BP). This study aimed to investigate the acute effects of cocoa beverage co-consumption with a high-fat-high-salt meal (HFHSM) on postprandial systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate in older adults living with uncontrolled hypertension. The study was a randomized crossover trial and involved older adults (aged 52.50 ± 9.36 years) (n = 28) living with hypertension. Participants, following an overnight fast, consumed either an HFHSM and cocoa beverage comprising 15 g cocoa powder in 250 mL water (HFHSM + CB; intervention) or HFHSM and 250 mL water (HFHSM + W; control). Resting SBP, DBP, and the heart rate of participants were measured at baseline (−5 min and 0 min) and 15, 30, 45, 60, 90, and 120 min following the consumption of either HFHSM + CB or HFHSM + W using an automated BP monitor. Repeated measures linear mixed model was used to compare the effect of cocoa beverage and water on postprandial outcomes over a 2-h period. A significant reduction (−3.8 ± 0.6 mmHg, < .05) in resting SBP was observed postprandially following the intake of the HFHSM + CB over the 120-min period compared to the HFHSM + W. The effect was more prominent during the 90- and 120-min time points of the trial duration. No significant change in the DBP and heart rate following the consumption of HFHSM + CB compared to the HFHSM + W was observed. Cocoa beverage co-consumption with HFHSM improved postprandial SBP in older adults living with hypertension.

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