Biocomputing in plants, from proof of concept to application

In response to the challenges of climate change and the transition toward sustainability, synthetic biology offers innovative solutions. Most current plant synthetic biology applications rely on the constitutive expression of enzymes and regulators. To engineer plant phenotypes tuneable to environmental conditions and plant cellular states, the integration of multiple signals in synthetic circuits is required. While most circuits are developed in model organisms, numerous tools were recently developed to implement biocomputation in plant synthetic circuits. I presented in this review the tools and design methods for logic circuit implementation in plants. I highlighted recent and potential applications of those circuits to understand and engineer plant interaction with the environment, development, and metabolic pathways.