使用长轴视场 PET/CT 系统进行 18F-FDG PET/CT 成像时的超低胎儿辐射量。

IF 3 2区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING EJNMMI Physics Pub Date : 2024-05-24 DOI:10.1186/s40658-024-00648-w

Charlotte L C Smith, Maqsood Yaqub, Ruud H H Wellenberg, Jelijn J Knip, Ronald Boellaard, Gerben J C Zwezerijnen

{"title":"使用长轴视场 PET/CT 系统进行 18F-FDG PET/CT 成像时的超低胎儿辐射量。","authors":"Charlotte L C Smith, Maqsood Yaqub, Ruud H H Wellenberg, Jelijn J Knip, Ronald Boellaard, Gerben J C Zwezerijnen","doi":"10.1186/s40658-024-00648-w","DOIUrl":null,"url":null,"abstract":"Purpose: Long axial field-of-view (LAFOV) PET/CT systems enable PET/CT scans with reduced injected activities because of improved sensitivity. With this study, we aimed to examine the foetal radiation dose from an 18F-FDG PET/CT scan on a LAFOV PET/CT system with reduced injected activity.Methods: Two pregnant women were retrospectively included and received an 18F-FDG PET/CT scan on a LAFOV PET/CT system with an intravenous bolus injection of 0.30 MBq/kg. Foetal radiation exposure from the PET was estimated using dose conversion factors from three published papers. Radiation exposure from the CT scans was estimated using CT-Expo.Results: Foetal radiation dose from the PET scan ranged between 0.11 and 0.44 mGy. Foetal radiation exposure from the CT scan ranged between < 0.10 - 0.90 mGy depending if the foetus was included in the field-of-view.Conclusion: Foetal radiation dose could be reduced to < 1.5 mGy when scanning pregnant patients on a LAFOV PET/CT system. The radiation dose to the foetus was reduced significantly in our study due to the increased sensitivity of the LAFOV PET/CT system.","PeriodicalId":11559,"journal":{"name":"EJNMMI Physics","volume":"11 1","pages":"45"},"PeriodicalIF":3.0000,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126546/pdf/","citationCount":"0","resultStr":"{\"title\":\"Ultra-low foetal radiation exposure in 18F-FDG PET/CT imaging with a long axial field-of-view PET/CT system.\",\"authors\":\"Charlotte L C Smith, Maqsood Yaqub, Ruud H H Wellenberg, Jelijn J Knip, Ronald Boellaard, Gerben J C Zwezerijnen\",\"doi\":\"10.1186/s40658-024-00648-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Purpose: Long axial field-of-view (LAFOV) PET/CT systems enable PET/CT scans with reduced injected activities because of improved sensitivity. With this study, we aimed to examine the foetal radiation dose from an 18F-FDG PET/CT scan on a LAFOV PET/CT system with reduced injected activity.Methods: Two pregnant women were retrospectively included and received an 18F-FDG PET/CT scan on a LAFOV PET/CT system with an intravenous bolus injection of 0.30 MBq/kg. Foetal radiation exposure from the PET was estimated using dose conversion factors from three published papers. Radiation exposure from the CT scans was estimated using CT-Expo.Results: Foetal radiation dose from the PET scan ranged between 0.11 and 0.44 mGy. Foetal radiation exposure from the CT scan ranged between < 0.10 - 0.90 mGy depending if the foetus was included in the field-of-view.Conclusion: Foetal radiation dose could be reduced to < 1.5 mGy when scanning pregnant patients on a LAFOV PET/CT system. The radiation dose to the foetus was reduced significantly in our study due to the increased sensitivity of the LAFOV PET/CT system.\",\"PeriodicalId\":11559,\"journal\":{\"name\":\"EJNMMI Physics\",\"volume\":\"11 1\",\"pages\":\"45\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-05-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126546/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"EJNMMI Physics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s40658-024-00648-w\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"EJNMMI Physics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s40658-024-00648-w","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}

引用次数: 0

摘要

目的：长轴向视场（LAFOV）PET/CT 系统由于提高了灵敏度，因此可以在降低注射活性的情况下进行 PET/CT 扫描。通过这项研究，我们旨在检查在注射活性降低的 LAFOV PET/CT 系统上进行 18F-FDG PET/CT 扫描时胎儿的辐射剂量：我们回顾性地纳入了两名孕妇，她们在 LAFOV PET/CT 系统上接受了 18F-FDG PET/CT 扫描，静脉注射了 0.30 MBq/kg。使用三篇已发表论文中的剂量换算系数估算了 PET 对胎儿的辐射量。CT扫描的辐射量是用CT-Expo.Results估算的：结果：PET 扫描产生的胎儿辐射剂量介于 0.11 和 0.44 mGy 之间。CT 扫描产生的胎儿辐射剂量介于 0.11 和 0.44 mGy 之间：胎儿辐射剂量可减少到

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Ultra-low foetal radiation exposure in ¹⁸F-FDG PET/CT imaging with a long axial field-of-view PET/CT system.

Purpose: Long axial field-of-view (LAFOV) PET/CT systems enable PET/CT scans with reduced injected activities because of improved sensitivity. With this study, we aimed to examine the foetal radiation dose from an ¹⁸F-FDG PET/CT scan on a LAFOV PET/CT system with reduced injected activity.

Methods: Two pregnant women were retrospectively included and received an ¹⁸F-FDG PET/CT scan on a LAFOV PET/CT system with an intravenous bolus injection of 0.30 MBq/kg. Foetal radiation exposure from the PET was estimated using dose conversion factors from three published papers. Radiation exposure from the CT scans was estimated using CT-Expo.

Results: Foetal radiation dose from the PET scan ranged between 0.11 and 0.44 mGy. Foetal radiation exposure from the CT scan ranged between < 0.10 - 0.90 mGy depending if the foetus was included in the field-of-view.

Conclusion: Foetal radiation dose could be reduced to < 1.5 mGy when scanning pregnant patients on a LAFOV PET/CT system. The radiation dose to the foetus was reduced significantly in our study due to the increased sensitivity of the LAFOV PET/CT system.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

EJNMMI Physics Physics and Astronomy-Radiation

CiteScore

6.70

自引率

10.00%

发文量

审稿时长

13 weeks

期刊介绍： EJNMMI Physics is an international platform for scientists, users and adopters of nuclear medicine with a particular interest in physics matters. As a companion journal to the European Journal of Nuclear Medicine and Molecular Imaging, this journal has a multi-disciplinary approach and welcomes original materials and studies with a focus on applied physics and mathematics as well as imaging systems engineering and prototyping in nuclear medicine. This includes physics-driven approaches or algorithms supported by physics that foster early clinical adoption of nuclear medicine imaging and therapy.