Fatal case of haemorrhagic fever with renal syndrome

The Far Eastern Federal District comprises an epidemic focus of hemorrhagic fever with renal syndrome (HFRS), where the incidence is determined by two orthohantaviruses: Hantaan (including its variant Amur) and Seoul. In Primorsky Krai, the average long-term incidence rate for 13 years (2011–2023) accounted for 2.7% (in some years up to 4.4% per 100 thousand population), and the mortality rate comprised 3.2% (9.1% in 2018). The distribution of clinical forms of the disease over the past 13 years revealed the prevalence of its moderate forms (66%), severe forms accounted for about 30% of all cases. The study presents a clinical case of severe course of HFRS with lethal outcome in a young male with no concomitant pathology.