Anush Kh. Khachatryan, Katya A. Avagyan, Anush A. Sargsyan, Anait G. Simonyan, Henrik A. Panosyan, Armen G. Ayvazyan, Alik E. Badasyan
{"title":"2-氨基-1-(芳基)-5-(芳基氨基甲酰基)-6-氧代-1,6-二氢吡啶-3-羧酸乙酯的合成","authors":"Anush Kh. Khachatryan, Katya A. Avagyan, Anush A. Sargsyan, Anait G. Simonyan, Henrik A. Panosyan, Armen G. Ayvazyan, Alik E. Badasyan","doi":"10.1007/s10593-024-03311-5","DOIUrl":null,"url":null,"abstract":"<p>A new method for the synthesis of previously unknown ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates by a reaction of ethyl 2-cyano-3-ethoxyacrylate with <i>N</i><sup>1</sup>,<i>N</i><sup>3</sup>-diarylmalonamides was developed. The antibacterial activity of some of the synthesized compounds was assayed.</p>","PeriodicalId":9770,"journal":{"name":"Chemistry of Heterocyclic Compounds","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The synthesis of ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates\",\"authors\":\"Anush Kh. Khachatryan, Katya A. Avagyan, Anush A. Sargsyan, Anait G. Simonyan, Henrik A. Panosyan, Armen G. Ayvazyan, Alik E. Badasyan\",\"doi\":\"10.1007/s10593-024-03311-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A new method for the synthesis of previously unknown ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates by a reaction of ethyl 2-cyano-3-ethoxyacrylate with <i>N</i><sup>1</sup>,<i>N</i><sup>3</sup>-diarylmalonamides was developed. The antibacterial activity of some of the synthesized compounds was assayed.</p>\",\"PeriodicalId\":9770,\"journal\":{\"name\":\"Chemistry of Heterocyclic Compounds\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-06-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemistry of Heterocyclic Compounds\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1007/s10593-024-03311-5\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry of Heterocyclic Compounds","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s10593-024-03311-5","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
The synthesis of ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates
A new method for the synthesis of previously unknown ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates by a reaction of ethyl 2-cyano-3-ethoxyacrylate with N1,N3-diarylmalonamides was developed. The antibacterial activity of some of the synthesized compounds was assayed.
期刊介绍:
The international journal Chemistry of Heterocyclic Compounds publishes original papers, short communications, reviews, and mini-reviews dealing with problems in the field of heterocyclic chemistry in Russian and English. The Journal also publishes reviews and annotations on new books and brief reports on conferences in the field of heterocyclic chemistry, as well as commemoratives dedicated to prominent heterocyclic chemists.