基于 RPCA 的热声成像技术用于微波消融监测

IF 7.1 1区 医学 Q1 ENGINEERING, BIOMEDICAL Photoacoustics Pub Date : 2024-05-31 DOI:10.1016/j.pacs.2024.100622
Fuyong Wang , Zeqi Yang , Wanting Peng , Ling Song , Yan Luo , Zhiqin Zhao , Lin Huang
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引用次数: 0

摘要

微波消融(MWA)是一种有效的癌症治疗工具,但由于缺乏视觉反馈,其有效性可能会受到影响。本文验证了使用微波诱导热声成像(TAI)技术监测微波消融过程的可行性。本文从原理层面进行了可行性分析,并介绍了一种高性能实时 TAI 系统。针对 MWA 造成的干扰,提出了一种基于鲁棒主成分分析 (RPCA) 的 TAI 方法。该方法利用多个信号帧之间的相关性来消除干扰。通过三组不同的实验证明了 RPCA 在 TAI 中的有效性。实验证明,TAI 可以有效监测 MWA 过程。这项工作代表了 RPCA 相关矩阵分解方法在 TAI 中的首次应用,为 TAI 在更复杂的临床场景中的应用铺平了道路。通过提供快速准确的视觉反馈,这项研究推动了 MWA 技术的发展。
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RPCA-based thermoacoustic imaging for microwave ablation monitoring

Microwave ablation (MWA) is a potent cancer treatment tool, but its effectiveness can be hindered by the lack of visual feedback. This paper validates the feasibility of using microwave-induced thermoacoustic imaging (TAI) technique to monitor the MWA process. A feasibility analysis was conducted at the principle level and a high-performance real-time TAI system was introduced. To address the interference caused by MWA, a robust principal component analysis (RPCA)-based method for TAI was proposed. This method leverages the correlation between multiple signal frames to eliminate interference. RPCA’s effectiveness in TAI was demonstrated through three sets of different experiments. Experiments demonstrated that TAI can effectively monitors the MWA process. This work represents the first application of RPCA-related matrix decomposition methods in TAI, paving the way for the application of TAI in more complex clinical scenarios. By providing rapid and accurate visual feedback, this research advances MWA technology.

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来源期刊
Photoacoustics
Photoacoustics Physics and Astronomy-Atomic and Molecular Physics, and Optics
CiteScore
11.40
自引率
16.50%
发文量
96
审稿时长
53 days
期刊介绍: The open access Photoacoustics journal (PACS) aims to publish original research and review contributions in the field of photoacoustics-optoacoustics-thermoacoustics. This field utilizes acoustical and ultrasonic phenomena excited by electromagnetic radiation for the detection, visualization, and characterization of various materials and biological tissues, including living organisms. Recent advancements in laser technologies, ultrasound detection approaches, inverse theory, and fast reconstruction algorithms have greatly supported the rapid progress in this field. The unique contrast provided by molecular absorption in photoacoustic-optoacoustic-thermoacoustic methods has allowed for addressing unmet biological and medical needs such as pre-clinical research, clinical imaging of vasculature, tissue and disease physiology, drug efficacy, surgery guidance, and therapy monitoring. Applications of this field encompass a wide range of medical imaging and sensing applications, including cancer, vascular diseases, brain neurophysiology, ophthalmology, and diabetes. Moreover, photoacoustics-optoacoustics-thermoacoustics is a multidisciplinary field, with contributions from chemistry and nanotechnology, where novel materials such as biodegradable nanoparticles, organic dyes, targeted agents, theranostic probes, and genetically expressed markers are being actively developed. These advanced materials have significantly improved the signal-to-noise ratio and tissue contrast in photoacoustic methods.
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