慢性咳嗽患者的含阿片类药物处方。

IF 3.3 3区医学 Q2 RESPIRATORY SYSTEM Therapeutic Advances in Respiratory Disease Pub Date : 2024-01-01 DOI:10.1177/17534666241259373

Michael Weiner, Ziyue Liu, Jonathan Schelfhout, Paul Dexter, Anna R Roberts, Ashley Griffith, Vishal Bali, Jessica Weaver

{"title":"慢性咳嗽患者的含阿片类药物处方。","authors":"Michael Weiner, Ziyue Liu, Jonathan Schelfhout, Paul Dexter, Anna R Roberts, Ashley Griffith, Vishal Bali, Jessica Weaver","doi":"10.1177/17534666241259373","DOIUrl":null,"url":null,"abstract":"Background: Chronic cough (CC) affects about 10% of adults, but opioid use in CC is not well understood.Objectives: To determine the use of opioid-containing cough suppressant (OCCS) prescriptions in patients with CC using electronic health records.Design: Retrospective cohort study.Methods: Through retrospective analysis of Midwestern U.S. electronic health records, diagnoses, prescriptions, and natural language processing identified CC - at least three medical encounters with cough, with 56-120 days between first and last encounter - and a 'non-chronic cohort'. Student's t-test, Pearson's chi-square, and zero-inflated Poisson models were used.Results: About 20% of 23,210 patients with CC were prescribed OCCS; odds of an OCCS prescription were twice as great in CC. In CC, OCCS drugs were ordered in 38% with Medicaid insurance and 15% with commercial insurance.Conclusion: Findings identify an important role for opioids in CC, and opportunity to learn more about the drugs' effectiveness.","PeriodicalId":22884,"journal":{"name":"Therapeutic Advances in Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11179543/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prescriptions of opioid-containing drugs in patients with chronic cough.\",\"authors\":\"Michael Weiner, Ziyue Liu, Jonathan Schelfhout, Paul Dexter, Anna R Roberts, Ashley Griffith, Vishal Bali, Jessica Weaver\",\"doi\":\"10.1177/17534666241259373\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Chronic cough (CC) affects about 10% of adults, but opioid use in CC is not well understood.Objectives: To determine the use of opioid-containing cough suppressant (OCCS) prescriptions in patients with CC using electronic health records.Design: Retrospective cohort study.Methods: Through retrospective analysis of Midwestern U.S. electronic health records, diagnoses, prescriptions, and natural language processing identified CC - at least three medical encounters with cough, with 56-120 days between first and last encounter - and a 'non-chronic cohort'. Student's t-test, Pearson's chi-square, and zero-inflated Poisson models were used.Results: About 20% of 23,210 patients with CC were prescribed OCCS; odds of an OCCS prescription were twice as great in CC. In CC, OCCS drugs were ordered in 38% with Medicaid insurance and 15% with commercial insurance.Conclusion: Findings identify an important role for opioids in CC, and opportunity to learn more about the drugs' effectiveness.\",\"PeriodicalId\":22884,\"journal\":{\"name\":\"Therapeutic Advances in Respiratory Disease\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11179543/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Therapeutic Advances in Respiratory Disease\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/17534666241259373\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutic Advances in Respiratory Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/17534666241259373","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}

引用次数: 0

摘要

背景：慢性咳嗽（CC）影响着约 10% 的成年人，但人们对慢性咳嗽患者使用阿片类药物的情况还不甚了解：利用电子健康记录确定慢性咳嗽患者使用含阿片类止咳药（OCCS）处方的情况：设计：回顾性队列研究：通过对美国中西部地区的电子健康记录、诊断、处方和自然语言处理进行回顾性分析，确定了CC（至少有三次咳嗽就诊经历，第一次和最后一次就诊间隔56-120天）和 "非慢性队列"。研究采用了学生 t 检验、皮尔逊卡方检验和零膨胀泊松模型：结果：在23210名CC患者中，约20%的患者开具了OCCS处方；CC患者开具OCCS处方的几率是其他患者的两倍。在CC中，38%的医疗补助保险患者和15%的商业保险患者开具了OCCS药物处方：研究结果表明，阿片类药物在CC中发挥着重要作用，我们有机会进一步了解这些药物的有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Prescriptions of opioid-containing drugs in patients with chronic cough.

Background: Chronic cough (CC) affects about 10% of adults, but opioid use in CC is not well understood.

Objectives: To determine the use of opioid-containing cough suppressant (OCCS) prescriptions in patients with CC using electronic health records.

Design: Retrospective cohort study.

Methods: Through retrospective analysis of Midwestern U.S. electronic health records, diagnoses, prescriptions, and natural language processing identified CC - at least three medical encounters with cough, with 56-120 days between first and last encounter - and a 'non-chronic cohort'. Student's t-test, Pearson's chi-square, and zero-inflated Poisson models were used.

Results: About 20% of 23,210 patients with CC were prescribed OCCS; odds of an OCCS prescription were twice as great in CC. In CC, OCCS drugs were ordered in 38% with Medicaid insurance and 15% with commercial insurance.

Conclusion: Findings identify an important role for opioids in CC, and opportunity to learn more about the drugs' effectiveness.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Therapeutic Advances in Respiratory Disease RESPIRATORY SYSTEM-

CiteScore

6.90

自引率

0.00%

发文量

审稿时长

15 weeks

期刊介绍： Therapeutic Advances in Respiratory Disease delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of respiratory disease.