中国杭州血小板球蛋白捐献者红细胞和铁研究数据分析

IF 1.4 4区医学 Q4 HEMATOLOGY Transfusion and Apheresis Science Pub Date : 2024-06-12 DOI:10.1016/j.transci.2024.103959

Chunyan Li , Zhongxiu Wu , Beijie Guo , Ruohua Ba , Haiyan Yang , Yinhong Zheng

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引用次数: 0

摘要

研究背景本研究的目的是了解献血者的铁指标水平以及需要关注铁指标水平的人群。结果血清铁蛋白（SF）水平偏低的男性和女性比例分别为 10.8%和 27.7%。男性献血者的血清铁（SI）、SF、转铁蛋白饱和度（Tfs）、血红蛋白（Hb）和血细胞比容（HCT）的平均水平随年龄组的增加而降低，但女性献血者的结果无明显统计学差异。男性献血者的 SI、SF、Tfs、Hb 和 HCT 水平随着过去一年献血量的增加而下降，而 TRF 和 TIBC 水平则上升。女性献血者的血红蛋白、血细胞比容和 SF 水平没有明显的下降趋势，而 TRF 水平则随着过去一年献血量的增加而上升，首次献血者除外。女性献血者的 SI 呈下降趋势，而 TIBC 则随着献血量的增加呈上升趋势。

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Analysis of erythrocyte and iron study data among plateletpheresis donors in Hangzhou, China

Background

The purpose of this study is to obtain the iron parameters level of blood donors and the population who need to pay attention to iron parameters level in this area.

Methods

A total of 993 plateletpheresis donors were included in this study, including 798 males and 195 females. The results of erythrocyte and iron parameters of blood donors were compared and analyzed in different groups according to the gender, age and number of blood donations.

Result

The proportion of men and women with low serum ferritin (SF) levels was 10.8 % and 27.7 %, respectively. The mean levels of serum iron (SI), SF, transferrin saturation (Tfs), hemoglobin (Hb) and hematocrit (HCT) of male blood donors decreased with the increase of age groups, but there was no significant statistical difference between the results of female blood donors. The level of SI, SF, Tfs, Hb and HCT of male donors decreased with the increase of blood donations in the past year, while TRF and TIBC increased. The level of Hb, HCT and SF of female donors showed no significant downward trend, while the levels of TRF increased with increasing donations in the past year, excluding first-time donors. The SI of female donors trended down, and TIBC trended up with increasing donations.

Conclusion

Blood collection institutions need to focus on iron parameters levels in older and frequent male donors, and young fertile female donors.

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来源期刊

Transfusion and Apheresis Science 医学-血液学

CiteScore

3.60

自引率

5.30%

发文量

181

审稿时长

42 days

期刊介绍： Transfusion and Apheresis Science brings comprehensive and up-to-date information to physicians and health care professionals involved in the rapidly changing fields of transfusion medicine, hemostasis and apheresis. The journal presents original articles relating to scientific and clinical studies in the areas of immunohematology, transfusion practice, bleeding and thrombotic disorders and both therapeutic and donor apheresis including hematopoietic stem cells. Topics covered include the collection and processing of blood, compatibility testing and guidelines for the use of blood products, as well as screening for and transmission of blood-borne diseases. All areas of apheresis - therapeutic and collection - are also addressed. We would like to specifically encourage allied health professionals in this area to submit manuscripts that relate to improved patient and donor care, technical aspects and educational issues. Transfusion and Apheresis Science features a "Theme" section which includes, in each issue, a group of papers designed to review a specific topic of current importance in transfusion and hemostasis for the discussion of topical issues specific to apheresis and focuses on the operators'' viewpoint. Another section is "What''s Happening" which provides informal reporting of activities in the field. In addition, brief case reports and Letters to the Editor, as well as reviews of meetings and events of general interest, and a listing of recent patents make the journal a complete source of information for practitioners of transfusion, hemostasis and apheresis science. Immediate dissemination of important information is ensured by the commitment of Transfusion and Apheresis Science to rapid publication of both symposia and submitted papers.