新型一氧化氮伤口敷料在犬急性创伤伤口中的应用。

IF 1.3 3区 农林科学 Q2 VETERINARY SCIENCES American journal of veterinary research Pub Date : 2024-06-27 DOI:10.2460/ajvr.24.04.0124
Sarah J Marvel, Benjamin Goldblatt, Catriona M MacPhail, Kristin M Zersen
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引用次数: 0

摘要

目的:描述一种新型伤口敷料的使用方法:描述一种新型伤口敷料的使用情况,这种敷料可为狗的自然创伤伤口提供一氧化氮(NO)。动物:24 只客户饲养的狗,共 30 处伤口:动物:24 只客户饲养的狗,共 30 处伤口。使用新型 NO 伤口敷料包扎伤口,并根据需要重新评估是否需要继续进行开放性伤口管理,直到伤口通过第二意向愈合或建议进行伤口缝合。临床医生可自行决定在任何时候将狗从研究中剔除:结果:在开放性伤口管理期间,所有伤口都使用了新型无伤口敷料,直到建议关闭伤口为止。伤口闭合的中位时间为 6 天(2 到 42 天不等)。使用新型伤口敷料后,犬只没有出现直接影响临床的并发症。有三处伤口在伤口缝合后开裂。有 19 只狗的 25 处伤口被证实愈合,其中 3 只狗在拆线前失去了随访机会。只有 7.1% 的伤口在伤口缝合后出现了符合伤口感染的临床症状:新型 NO 伤口敷料易于使用,在狗的自然创伤伤口中耐受性良好。它可用于伤口愈合的所有阶段,简化了开放性伤口的管理。
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The use of a novel nitric oxide wound dressing in acute traumatic wounds in dogs.

Objective: To describe the use of a novel wound dressing that delivers nitric oxide (NO) to naturally occurring traumatic wounds in dogs.

Animals: 24 client-owned dogs with 30 wounds.

Methods: Dogs were presented with acute traumatic wounds requiring open wound management. Wounds were bandaged with a novel NO wound dressing and reassessed as needed for continued open wound management until wounds healed by second intention or wound closure was recommended. Dogs could be removed from the study at any point at the clinician's discretion.

Results: All wounds had the novel NO wound dressing used during open wound management until wound closure was recommended. Median time to wound closure was 6 days (range, 2 to 42). There were no complications directly attributed to the use of the novel wound dressing that clinically affected the dogs. Three wounds dehisced following wound closure. Wound healing was confirmed in 19 dogs with 25 wounds, with 3 dogs lost to follow-up prior to suture removal. Only 7.1% of wounds had clinical signs consistent with wound infection following wound closure.

Clinical relevance: The novel NO wound dressing was easy to use and well tolerated in dogs with naturally occurring traumatic wounds. It can be used throughout all phases of wound healing, simplifying open wound management.

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来源期刊
CiteScore
1.70
自引率
10.00%
发文量
186
审稿时长
3 months
期刊介绍: The American Journal of Veterinary Research supports the collaborative exchange of information between researchers and clinicians by publishing novel research findings that bridge the gulf between basic research and clinical practice or that help to translate laboratory research and preclinical studies to the development of clinical trials and clinical practice. The journal welcomes submission of high-quality original studies and review articles in a wide range of scientific fields, including anatomy, anesthesiology, animal welfare, behavior, epidemiology, genetics, heredity, infectious disease, molecular biology, oncology, pharmacology, pathogenic mechanisms, physiology, surgery, theriogenology, toxicology, and vaccinology. Species of interest include production animals, companion animals, equids, exotic animals, birds, reptiles, and wild and marine animals. Reports of laboratory animal studies and studies involving the use of animals as experimental models of human diseases are considered only when the study results are of demonstrable benefit to the species used in the research or to another species of veterinary interest. Other fields of interest or animals species are not necessarily excluded from consideration, but such reports must focus on novel research findings. Submitted papers must make an original and substantial contribution to the veterinary medicine knowledge base; preliminary studies are not appropriate.
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