Jialin Wang , Yaqing Yang , Aaron Albert Aryee, Ningning Wang, Zhaohui Li
{"title":"用于高灵敏度检测食品污染物偶氮二甲酰胺的石墨烯量子点功能化上转换纳米粒子","authors":"Jialin Wang , Yaqing Yang , Aaron Albert Aryee, Ningning Wang, Zhaohui Li","doi":"10.1016/j.foodcont.2024.110680","DOIUrl":null,"url":null,"abstract":"<div><p>Excessive consumption of flour products containing excessive azodicarbonamide (ADA) has been associated with some adverse effects in humans. Thus, developing a facile method to monitor the amount of ADA in flour is extremely significant. Herein, a graphene quantum dot (GQD) sensitized upconversion nanoparticles (GQD-UCNPs) was designed to monitor the amount of ADA in flour with high specificity and sensitivity. Surface coating of UCNPs with GQD by coordination interaction significantly enhances the upconversion luminescence (UCL) intensity and the water solubility of UCNPs. Copper ions (Cu<sup>2+</sup>) can quench the UCL intensity of GQD-UCNPs through electron transfer processes. After introduction of glutathione (GSH), the UCL intensity of GQD-UCNPs gradually increases because of the interaction between GSH and Cu<sup>2+</sup>, accompanied by the generation of Cu<sup>+</sup>. The sulfydryl group of GSH can be oxidized to disulfide bond by ADA, which hinders the interaction between GSH and Cu<sup>2+</sup>, preventing the recovery of UCL intensity. Thus, the presence of ADA decreases the UCL intensity of GQD-UCNPs + Cu<sup>2+</sup> + GSH system, allowing for the quantitative detection of ADA. The nanosensor realized a highly sensitive and specific ADA detection with a high detection limit down to 0.055 μM. Furthermore, excellent recovery rates in spiked real samples were obtained, indicating that the designed method possesses good prospects for practical application. Notably, this method broadens the application prospects of upconversion technology in the field of food safety.</p></div>","PeriodicalId":319,"journal":{"name":"Food Control","volume":null,"pages":null},"PeriodicalIF":5.6000,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Graphene quantum dot-functionalized upconversion nanoparticles for highly sensitive detection of food contaminant azodicarbonamide\",\"authors\":\"Jialin Wang , Yaqing Yang , Aaron Albert Aryee, Ningning Wang, Zhaohui Li\",\"doi\":\"10.1016/j.foodcont.2024.110680\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Excessive consumption of flour products containing excessive azodicarbonamide (ADA) has been associated with some adverse effects in humans. Thus, developing a facile method to monitor the amount of ADA in flour is extremely significant. Herein, a graphene quantum dot (GQD) sensitized upconversion nanoparticles (GQD-UCNPs) was designed to monitor the amount of ADA in flour with high specificity and sensitivity. Surface coating of UCNPs with GQD by coordination interaction significantly enhances the upconversion luminescence (UCL) intensity and the water solubility of UCNPs. Copper ions (Cu<sup>2+</sup>) can quench the UCL intensity of GQD-UCNPs through electron transfer processes. After introduction of glutathione (GSH), the UCL intensity of GQD-UCNPs gradually increases because of the interaction between GSH and Cu<sup>2+</sup>, accompanied by the generation of Cu<sup>+</sup>. The sulfydryl group of GSH can be oxidized to disulfide bond by ADA, which hinders the interaction between GSH and Cu<sup>2+</sup>, preventing the recovery of UCL intensity. Thus, the presence of ADA decreases the UCL intensity of GQD-UCNPs + Cu<sup>2+</sup> + GSH system, allowing for the quantitative detection of ADA. The nanosensor realized a highly sensitive and specific ADA detection with a high detection limit down to 0.055 μM. Furthermore, excellent recovery rates in spiked real samples were obtained, indicating that the designed method possesses good prospects for practical application. Notably, this method broadens the application prospects of upconversion technology in the field of food safety.</p></div>\",\"PeriodicalId\":319,\"journal\":{\"name\":\"Food Control\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":5.6000,\"publicationDate\":\"2024-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food Control\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0956713524003979\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Control","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0956713524003979","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
Graphene quantum dot-functionalized upconversion nanoparticles for highly sensitive detection of food contaminant azodicarbonamide
Excessive consumption of flour products containing excessive azodicarbonamide (ADA) has been associated with some adverse effects in humans. Thus, developing a facile method to monitor the amount of ADA in flour is extremely significant. Herein, a graphene quantum dot (GQD) sensitized upconversion nanoparticles (GQD-UCNPs) was designed to monitor the amount of ADA in flour with high specificity and sensitivity. Surface coating of UCNPs with GQD by coordination interaction significantly enhances the upconversion luminescence (UCL) intensity and the water solubility of UCNPs. Copper ions (Cu2+) can quench the UCL intensity of GQD-UCNPs through electron transfer processes. After introduction of glutathione (GSH), the UCL intensity of GQD-UCNPs gradually increases because of the interaction between GSH and Cu2+, accompanied by the generation of Cu+. The sulfydryl group of GSH can be oxidized to disulfide bond by ADA, which hinders the interaction between GSH and Cu2+, preventing the recovery of UCL intensity. Thus, the presence of ADA decreases the UCL intensity of GQD-UCNPs + Cu2+ + GSH system, allowing for the quantitative detection of ADA. The nanosensor realized a highly sensitive and specific ADA detection with a high detection limit down to 0.055 μM. Furthermore, excellent recovery rates in spiked real samples were obtained, indicating that the designed method possesses good prospects for practical application. Notably, this method broadens the application prospects of upconversion technology in the field of food safety.
期刊介绍:
Food Control is an international journal that provides essential information for those involved in food safety and process control.
Food Control covers the below areas that relate to food process control or to food safety of human foods:
• Microbial food safety and antimicrobial systems
• Mycotoxins
• Hazard analysis, HACCP and food safety objectives
• Risk assessment, including microbial and chemical hazards
• Quality assurance
• Good manufacturing practices
• Food process systems design and control
• Food Packaging technology and materials in contact with foods
• Rapid methods of analysis and detection, including sensor technology
• Codes of practice, legislation and international harmonization
• Consumer issues
• Education, training and research needs.
The scope of Food Control is comprehensive and includes original research papers, authoritative reviews, short communications, comment articles that report on new developments in food control, and position papers.