Natasha L Hungerford, Diane Ouwerkerk, Rosalind A Gilbert, Zhi Hung Loh, Russell J Gordon, Luis F P Silva, Mary T Fletcher
{"title":"一项饲喂试验,旨在研究减轻澳大利亚牛皮米莱中毒影响的策略。","authors":"Natasha L Hungerford, Diane Ouwerkerk, Rosalind A Gilbert, Zhi Hung Loh, Russell J Gordon, Luis F P Silva, Mary T Fletcher","doi":"10.1021/acs.jafc.4c02082","DOIUrl":null,"url":null,"abstract":"<p><p><i>Pimelea</i> poisoning of cattle causes distinct symptoms and frequently death, attributable to the toxin simplexin. <i>Pimelea</i> poisoning was induced via addition of ground <i>Pimelea trichostachya</i> plant to the daily feed in a three-month trial with Droughtmaster steers. The trial tested four potential mitigation treatments, namely, biochar, activated biochar, bentonite, and a bacterial inoculum, and incorporated negative and positive control groups. All treatments tested were unable to prevent the development of simplexin poisoning effects. However, steers consuming a bentonite adsorbent together with <i>Pimelea</i> showed lesser rates-of-decline for body weight (<i>P</i> < 0.05) and four hematological parameters (<i>P</i> < 0.02), compared to the positive control group fed <i>Pimelea</i> only. Microbiome analysis revealed that despite displaying poisoning symptoms, the rumen microbial populations of animals receiving <i>Pimelea</i> were very resilient, with dominant bacterial populations maintained over time. Unexpectedly, clinical edema developed in some animals up to 2 weeks after <i>Pimelea</i> dosing was ceased.</p>","PeriodicalId":41,"journal":{"name":"Journal of Agricultural and Food Chemistry","volume":null,"pages":null},"PeriodicalIF":5.7000,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Feeding Trial to Investigate Strategies to Mitigate the Impacts of <i>Pimelea</i> Poisoning in Australian Cattle.\",\"authors\":\"Natasha L Hungerford, Diane Ouwerkerk, Rosalind A Gilbert, Zhi Hung Loh, Russell J Gordon, Luis F P Silva, Mary T Fletcher\",\"doi\":\"10.1021/acs.jafc.4c02082\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Pimelea</i> poisoning of cattle causes distinct symptoms and frequently death, attributable to the toxin simplexin. <i>Pimelea</i> poisoning was induced via addition of ground <i>Pimelea trichostachya</i> plant to the daily feed in a three-month trial with Droughtmaster steers. The trial tested four potential mitigation treatments, namely, biochar, activated biochar, bentonite, and a bacterial inoculum, and incorporated negative and positive control groups. All treatments tested were unable to prevent the development of simplexin poisoning effects. However, steers consuming a bentonite adsorbent together with <i>Pimelea</i> showed lesser rates-of-decline for body weight (<i>P</i> < 0.05) and four hematological parameters (<i>P</i> < 0.02), compared to the positive control group fed <i>Pimelea</i> only. Microbiome analysis revealed that despite displaying poisoning symptoms, the rumen microbial populations of animals receiving <i>Pimelea</i> were very resilient, with dominant bacterial populations maintained over time. Unexpectedly, clinical edema developed in some animals up to 2 weeks after <i>Pimelea</i> dosing was ceased.</p>\",\"PeriodicalId\":41,\"journal\":{\"name\":\"Journal of Agricultural and Food Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":5.7000,\"publicationDate\":\"2024-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Agricultural and Food Chemistry\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1021/acs.jafc.4c02082\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"AGRICULTURE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Agricultural and Food Chemistry","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1021/acs.jafc.4c02082","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"AGRICULTURE, MULTIDISCIPLINARY","Score":null,"Total":0}
A Feeding Trial to Investigate Strategies to Mitigate the Impacts of Pimelea Poisoning in Australian Cattle.
Pimelea poisoning of cattle causes distinct symptoms and frequently death, attributable to the toxin simplexin. Pimelea poisoning was induced via addition of ground Pimelea trichostachya plant to the daily feed in a three-month trial with Droughtmaster steers. The trial tested four potential mitigation treatments, namely, biochar, activated biochar, bentonite, and a bacterial inoculum, and incorporated negative and positive control groups. All treatments tested were unable to prevent the development of simplexin poisoning effects. However, steers consuming a bentonite adsorbent together with Pimelea showed lesser rates-of-decline for body weight (P < 0.05) and four hematological parameters (P < 0.02), compared to the positive control group fed Pimelea only. Microbiome analysis revealed that despite displaying poisoning symptoms, the rumen microbial populations of animals receiving Pimelea were very resilient, with dominant bacterial populations maintained over time. Unexpectedly, clinical edema developed in some animals up to 2 weeks after Pimelea dosing was ceased.
期刊介绍:
The Journal of Agricultural and Food Chemistry publishes high-quality, cutting edge original research representing complete studies and research advances dealing with the chemistry and biochemistry of agriculture and food. The Journal also encourages papers with chemistry and/or biochemistry as a major component combined with biological/sensory/nutritional/toxicological evaluation related to agriculture and/or food.