涉及自由基途径的光化学和电化学有机转化:回顾我们在绿色化学启发下的合成努力

IF 1.7 4区 化学 Q3 CHEMISTRY, ORGANIC Synlett Pub Date : 2024-07-08 DOI:10.1055/s-0043-1775382
Goutam Brahmachari
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引用次数: 0

摘要

本报告总结了我们最近(2020 年至 2024 年中期)在设计和开发一些有前景的有机转化过程方面所做的努力,这些转化过程遵循绿色化学原则,特别注重低能可见光和电化学的应用,从而获得了多种具有生物相关性的功能化有机支架。对每个反应的机理研究都确定了自由基途径的参与。1 引言 2 绿色灵感有机转化 2.1 可见光驱动的有机合成 2.1.1 功能化二氢呋喃并[3,2-c]苯并吡喃酮的合成 2.1.2 官能化 2-(芳基/烷基氨基)-3-(芳基/烷基硫代)萘-1,4-二酮和 2-(芳基氨基)-3-(芳基硫代)萘-1,4-二酮的合成 2.1.3 官能化 6-(芳硫基/芳硒基)苯并[a]酚-5-醇的合成 2.1.4 官能化 3-(烷基/苄硫基)-4-羟基-2H-苯并吡喃-2-酮的合成 2.1.5 功能化 2-羟基-3-氧代-2,3-二氢苯并呋喃-2-甲酰胺和 2-羟基-3-氧代-2,3-二氢苯并呋喃-2-甲酸酯的合成 2.1.6 功能化 2-羟基苯基化 α-酮酰胺的合成 2.2 电化学有机合成 2.2.1 2-氨基-1,4-萘醌的 3-硒化/亚砜化衍生物的合成 2.2.2 功能化 6-(芳硫基/芳硒基)苯并[a]酚-5-醇的合成 2.2.3 功能化 2-羟基-3-氧代-2,3-二氢苯并呋喃-2-甲酸烷基酯的合成 3 结论
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Photo- and Electrochemical Organic Transformations Involving Radical Pathway: A Retrospection of Our Green-Chemistry-Inspired Synthetic Endeavours

This account summarises our recent efforts (2020 to mid-2024) in designing and developing a handful of promising organic transformations for accessing several diversely functionalized biologically relevant organic scaffolds by following the green-chemistry principles with a particular focus on the application of low-energy visible light and electrochemistry. Mechanistic studies of each of these reactions established the involvement of a radical pathway.

1 Introduction

2 Green-Inspired Organic Transformations

2.1 Visible-Light-Driven Organic Synthesis

2.1.1 Synthesis of Functionalized Dihydrofuro[3,2-c]chromenones

2.1.2 Synthesis of Functionalized 2-(Aryl/alkylamino)-3-(aryl/alkylselanyl)naphthalene-1,4-diones and 2-(Arylamino)-3-(arylthio)naphthalene-1,4-diones

2.1.3 Synthesis of Functionalized 6-(Arylthio/arylseleno)benzo[a]phenazin-5-ols

2.1.4 Synthesis of Functionalized 3-(Alkyl/benzylthio)-4-hydroxy-2H-chromen-2-ones

2.1.5 Synthesis of Functionalized 2-Hydroxy-3-oxo-2,3-dihydrobenzofuran-2-carboxamides and 2-Hydroxy-3-oxo-2,3-dihydrobenzofuran-2-carboxylates

2.1.6 Synthesis of Functionalized 2-Hydroxyphenylated α-Ketoamides

2.2 Electrochemical Organic Synthesis

2.2.1 Synthesis of 3-Selenylated/Sulfenylated Derivatives of 2-Amino-1,4-naphthoquinones

2.2.2 Synthesis of Functionalized 6-(Arylthio/Arylseleno)benzo[a]phenazin-5-ols

2.2.3 Synthesis of Functionalized Alkyl 2-Hydroxy-3-oxo-2,3-dihydrobenzofuran-2-carboxylates

3 Conclusions

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来源期刊
Synlett
Synlett 化学-有机化学
CiteScore
3.40
自引率
5.00%
发文量
369
审稿时长
1 months
期刊介绍: SYNLETT is an international journal reporting research results and current trends in chemical synthesis in short personalized reviews and preliminary communications. It covers all fields of scientific endeavor that involve organic synthesis, including catalysis, organometallic, medicinal, biological, and photochemistry, but also related disciplines and offers the possibility to publish scientific primary data.
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