利用基于熵的特征和多模型深度学习方法自动诊断癫痫发作

IF 1.7 4区 医学 Q3 ENGINEERING, BIOMEDICAL Medical Engineering & Physics Pub Date : 2024-07-05 DOI:10.1016/j.medengphy.2024.104206
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引用次数: 0

摘要

癫痫是最常见的脑部疾病之一,其特点是定期反复发作。癫痫发作时,患者的肌肉会不受控制地弯曲,导致行动不便和失去平衡,这可能对患者造成伤害,甚至致命。开发一种自动方法,在癫痫即将发作时向患者发出警告,这需要进行大量研究。分析人脑头皮区域的脑电图(EEG)输出有助于预测癫痫发作。分析脑电图数据可提取时域特征,如赫斯特指数(Hur)、查利斯熵(TsEn)、增强排列熵(impe)和振幅感知排列熵(AAPE)。为了从正常儿童中自动诊断儿童癫痫发作,本研究进行了两次分析。在第一个环节中,使用三种基于机器学习(ML)的模型,包括支持向量机(SVM)、K 近邻(KNN)或决策树(DT),对从脑电图数据集中提取的特征进行分类;在第二个环节中,使用三种基于深度学习(DL)的循环神经网络(RNN)分类器,对数据集进行分类。 脑电图数据集来自伊本鲁什德培训医院的神经病学诊所。在这方面,来自时域和熵特征的大量解释和研究表明,在全时熵融合特征上采用 GRU、LSTM 和 BiLSTM RNN 深度学习分类器可以改善最终的分类结果。
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Automatic diagnosis of epileptic seizures using entropy-based features and multimodel deep learning approaches

Epilepsy is one of the most common brain diseases, characterised by repeated seizures that occur on a regular basis. During a seizure, a patient's muscles flex uncontrollably, causing a loss of mobility and balance, which can be harmful or even fatal. Developing an automatic approach for warning patients of oncoming seizures necessitates substantial research. Analyzing the electroencephalogram (EEG) output from the human brain's scalp region can help predict seizures. EEG data were analyzed to extract time domain features such as Hurst exponent (Hur), Tsallis entropy (TsEn), enhanced permutation entropy (impe), and amplitude-aware permutation entropy (AAPE). In order to automatically diagnose epileptic seizure in children from normal children, this study conducted two sessions. In the first session, the extracted features from the EEG dataset were classified using three machine learning (ML)-based models, including support vector machine (SVM), K nearest neighbor (KNN), or decision tree (DT), and in the second session, the dataset was classified using three deep learning (DL)-based recurrent neural network (RNN) classifiers in The EEG dataset was obtained from the Neurology Clinic of the Ibn Rushd Training Hospital. In this regard, extensive explanations and research from the time domain and entropy characteristics demonstrate that employing GRU, LSTM, and BiLSTM RNN deep learning classifiers on the Alltimeentropy fusion feature improves the final classification results.

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来源期刊
Medical Engineering & Physics
Medical Engineering & Physics 工程技术-工程:生物医学
CiteScore
4.30
自引率
4.50%
发文量
172
审稿时长
3.0 months
期刊介绍: Medical Engineering & Physics provides a forum for the publication of the latest developments in biomedical engineering, and reflects the essential multidisciplinary nature of the subject. The journal publishes in-depth critical reviews, scientific papers and technical notes. Our focus encompasses the application of the basic principles of physics and engineering to the development of medical devices and technology, with the ultimate aim of producing improvements in the quality of health care.Topics covered include biomechanics, biomaterials, mechanobiology, rehabilitation engineering, biomedical signal processing and medical device development. Medical Engineering & Physics aims to keep both engineers and clinicians abreast of the latest applications of technology to health care.
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